First molecular characterization and phylogenetic analysis of the VP2 gene of feline panleukopenia virus in Bangladesh

Q. M.Monzur Kader Chowdhury, Shahrul Alam, Md Shahidur Rahman Chowdhury, Mahmudul Hasan, Md Bashir Uddin, Md Mukter Hossain, Md Rafiqul Islam, Md Masudur Rahman, Md Mahfujur Rahman

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Feline panleukopenia virus (FPV) is a highly contagious infectious pathogen of cats globally. However, there is no information on the molecular identification and characterization of FPV in Bangladesh. Here, 8.16% (8/98) and 18.37% (18/98) of diarrheic cats tested positive for FPV by an immunochromatography (IC) test and PCR, respectively. The IC test showed 44.44% sensitivity and 100% specificity in comparison with PCR. Our newly sequenced Bangladeshi FPV strain (MN826076) showed the highest (99.71%) sequence identity to strains from the United Arab Emirates (UAE). Strain MN826076 contained two characteristic amino acid variations in VP2 identifying it as an FPV strain: valine at position 103 and aspartic acid at position 323. Phylogenetically, the VP2 of strain MN826076 was found to be closely related to 19 FPV strains, sharing the same clade.

Original languageEnglish (US)
Pages (from-to)2273-2278
Number of pages6
JournalArchives of virology
Volume166
Issue number8
DOIs
StatePublished - Aug 2021
Externally publishedYes

ASJC Scopus subject areas

  • Virology

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