First report on application of diode laser for photocoagulation of canine myocardium

David L.MD Ware, Massoud Motamedi, John Pohl, Brent A. Bell, Paul MD Boor

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Ventricular tachycardia (VT) is a rapid heart rhythm which is often life threatening. Several surgical and percutaneous ways to destroy the myocardium responsible for VT have been studied. It has been postulated that laser therapy may be ideal for this purpose because it can heat a large volume of tissue. Recent developments in diode lasers have prompted us to evaluate this source (810 nm) for photocoagulation of myocardial tissue. Its size, ease of maintenance, and cost make diode laser suitable for clinical practice in general, and for percutaneous photoablation in particular. Lesions were created in myocardium with contact irradiation using a 600 micron bare tipped optical fiber both in vitro and in vivo. Exposures of 2 to 3 W over 30 to 60 seconds created lesions with no or minimal char formations. In vivo lesions tended to be larger than in vitro, with better defined border zones. Animals tolerated laser irradiation well without significant ventricular ectopy. Diode laser irradiation is a promising means to percutaneously coagulate ventricular myocardium and for cure of VT. Further investigation of the dosimetry and healing response in both healthy and diseased myocardium is warranted.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsGeorge S. Abela
Pages150-155
Number of pages6
StatePublished - Dec 1 1994
EventProceedings of Diagnostic and Therapeutic Cardiovascular Interventions IV - Los Angeles, CA, USA
Duration: Jan 22 1994Jan 23 1994

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume2130
ISSN (Print)0277-786X

Other

OtherProceedings of Diagnostic and Therapeutic Cardiovascular Interventions IV
CityLos Angeles, CA, USA
Period1/22/941/23/94

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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  • Cite this

    Ware, D. L. MD., Motamedi, M., Pohl, J., Bell, B. A., & Boor, P. MD. (1994). First report on application of diode laser for photocoagulation of canine myocardium. In G. S. Abela (Ed.), Proceedings of SPIE - The International Society for Optical Engineering (pp. 150-155). (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 2130).