Flavitrack: An annotated database of flavivirus sequences

Milind Misra; Catherine H. Schein

doi:10.1093/bioinformatics/btm383

Flavitrack: An annotated database of flavivirus sequences

Milind Misra, Catherine H. Schein

Biochemistry & Molecular Biology

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

Motivation: Properly annotated sequence data for flaviviruses, which cause diseases, such as tick-borne encephalitis (TBE), dengue fever (DF), West Nile (WN) and yellow fever (YF), can aid in the design of antiviral drugs and vaccines to prevent their spread. Flavitrack was designed to help identify conserved sequence motifs, interpret mutational and structural data and track evolution of phenotypic properties. Summary: Flavitrack contains over 590 complete flavivirus genome/protein sequences and information on known mutations and literature references. Each sequence has been manually annotated according to its date and place of isolation, phenotype and lethality. Internal tools are provided to rapidly determine relationships between viruses in Flavitrack and sequences provided by the user.

Original language	English (US)
Pages (from-to)	2645-2647
Number of pages	3
Journal	Bioinformatics
Volume	23
Issue number	19
DOIs	https://doi.org/10.1093/bioinformatics/btm383
State	Published - Oct 1 2007

ASJC Scopus subject areas

Statistics and Probability
Biochemistry
Molecular Biology
Computer Science Applications
Computational Theory and Mathematics
Computational Mathematics

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10.1093/bioinformatics/btm383

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abstract = "Motivation: Properly annotated sequence data for flaviviruses, which cause diseases, such as tick-borne encephalitis (TBE), dengue fever (DF), West Nile (WN) and yellow fever (YF), can aid in the design of antiviral drugs and vaccines to prevent their spread. Flavitrack was designed to help identify conserved sequence motifs, interpret mutational and structural data and track evolution of phenotypic properties. Summary: Flavitrack contains over 590 complete flavivirus genome/protein sequences and information on known mutations and literature references. Each sequence has been manually annotated according to its date and place of isolation, phenotype and lethality. Internal tools are provided to rapidly determine relationships between viruses in Flavitrack and sequences provided by the user.",

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Flavitrack: An annotated database of flavivirus sequences

Abstract

ASJC Scopus subject areas

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