Flavivirus NS5 prevents the InSTATement of IFN

Pei Yong Shi

Research output: Contribution to journalShort surveypeer-review

13 Scopus citations


Given the potency of interferon-α/β, viral evasion of this pathway is crucial for infection. In this issue of Cell Host & Microbe, Laurent-Rolle et al. (2014) report that during yellow fever virus infection, interferon-α/β stimulates the polyubiquitination of viral NS5, which binds to STAT2 and inhibits transcription of interferon-stimulated genes.

Original languageEnglish (US)
Pages (from-to)269-271
Number of pages3
JournalCell Host and Microbe
Issue number3
StatePublished - Sep 10 2014

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Virology


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