Flawed experimental design reveals the need for guidelines requiring appropriate positive controls in endocrine disruption research

Frederick S. vom Saal, Benson T. Akingbemi, Scott M. Belcher, David A. Crain, David Crews, Linda C. Guidice, Patricia A. Hunt, Csaba Leranth, John Peterson Myers, Angel Nadal, Nicholas Olea, Vasantha Padmanabhan, Cheryl S. Rosenfeld, Alan Schneyer, Gilbert Schoenfelder, Carlos Sonnenschein, Ana M. Soto, Richard W. Stahlhut, Shanna H. Swan, Laura N. Vandenberg & 4 others Hong Sheng Wang, Cheryl S. Watson, Wade V. Welshons, Robert T. Zoeller

    Research output: Contribution to journalArticle

    50 Citations (Scopus)
    Original languageEnglish (US)
    Pages (from-to)612-613
    Number of pages2
    JournalToxicological Sciences
    Volume115
    Issue number2
    DOIs
    StatePublished - Feb 17 2010

    Fingerprint

    Drug Dose Response Relationship
    Non-Steroidal Estrogens
    Female Genitalia
    Endocrine Disruptors
    Maternal Exposure
    No-Observed-Adverse-Effect Level
    Toxicity Tests
    Long Evans Rats
    Ethinyl Estradiol
    Fertility
    Research Design
    Guidelines
    Pregnancy
    Research

    ASJC Scopus subject areas

    • Toxicology

    Cite this

    vom Saal, F. S., Akingbemi, B. T., Belcher, S. M., Crain, D. A., Crews, D., Guidice, L. C., ... Zoeller, R. T. (2010). Flawed experimental design reveals the need for guidelines requiring appropriate positive controls in endocrine disruption research. Toxicological Sciences, 115(2), 612-613. https://doi.org/10.1093/toxsci/kfq048

    Flawed experimental design reveals the need for guidelines requiring appropriate positive controls in endocrine disruption research. / vom Saal, Frederick S.; Akingbemi, Benson T.; Belcher, Scott M.; Crain, David A.; Crews, David; Guidice, Linda C.; Hunt, Patricia A.; Leranth, Csaba; Myers, John Peterson; Nadal, Angel; Olea, Nicholas; Padmanabhan, Vasantha; Rosenfeld, Cheryl S.; Schneyer, Alan; Schoenfelder, Gilbert; Sonnenschein, Carlos; Soto, Ana M.; Stahlhut, Richard W.; Swan, Shanna H.; Vandenberg, Laura N.; Wang, Hong Sheng; Watson, Cheryl S.; Welshons, Wade V.; Zoeller, Robert T.

    In: Toxicological Sciences, Vol. 115, No. 2, 17.02.2010, p. 612-613.

    Research output: Contribution to journalArticle

    vom Saal, FS, Akingbemi, BT, Belcher, SM, Crain, DA, Crews, D, Guidice, LC, Hunt, PA, Leranth, C, Myers, JP, Nadal, A, Olea, N, Padmanabhan, V, Rosenfeld, CS, Schneyer, A, Schoenfelder, G, Sonnenschein, C, Soto, AM, Stahlhut, RW, Swan, SH, Vandenberg, LN, Wang, HS, Watson, CS, Welshons, WV & Zoeller, RT 2010, 'Flawed experimental design reveals the need for guidelines requiring appropriate positive controls in endocrine disruption research', Toxicological Sciences, vol. 115, no. 2, pp. 612-613. https://doi.org/10.1093/toxsci/kfq048
    vom Saal, Frederick S. ; Akingbemi, Benson T. ; Belcher, Scott M. ; Crain, David A. ; Crews, David ; Guidice, Linda C. ; Hunt, Patricia A. ; Leranth, Csaba ; Myers, John Peterson ; Nadal, Angel ; Olea, Nicholas ; Padmanabhan, Vasantha ; Rosenfeld, Cheryl S. ; Schneyer, Alan ; Schoenfelder, Gilbert ; Sonnenschein, Carlos ; Soto, Ana M. ; Stahlhut, Richard W. ; Swan, Shanna H. ; Vandenberg, Laura N. ; Wang, Hong Sheng ; Watson, Cheryl S. ; Welshons, Wade V. ; Zoeller, Robert T. / Flawed experimental design reveals the need for guidelines requiring appropriate positive controls in endocrine disruption research. In: Toxicological Sciences. 2010 ; Vol. 115, No. 2. pp. 612-613.
    @article{a85d9d4ed59b4ac0b6f44b96fc132c8d,
    title = "Flawed experimental design reveals the need for guidelines requiring appropriate positive controls in endocrine disruption research",
    author = "{vom Saal}, {Frederick S.} and Akingbemi, {Benson T.} and Belcher, {Scott M.} and Crain, {David A.} and David Crews and Guidice, {Linda C.} and Hunt, {Patricia A.} and Csaba Leranth and Myers, {John Peterson} and Angel Nadal and Nicholas Olea and Vasantha Padmanabhan and Rosenfeld, {Cheryl S.} and Alan Schneyer and Gilbert Schoenfelder and Carlos Sonnenschein and Soto, {Ana M.} and Stahlhut, {Richard W.} and Swan, {Shanna H.} and Vandenberg, {Laura N.} and Wang, {Hong Sheng} and Watson, {Cheryl S.} and Welshons, {Wade V.} and Zoeller, {Robert T.}",
    year = "2010",
    month = "2",
    day = "17",
    doi = "10.1093/toxsci/kfq048",
    language = "English (US)",
    volume = "115",
    pages = "612--613",
    journal = "Toxicological Sciences",
    issn = "1096-6080",
    publisher = "Oxford University Press",
    number = "2",

    }

    TY - JOUR

    T1 - Flawed experimental design reveals the need for guidelines requiring appropriate positive controls in endocrine disruption research

    AU - vom Saal, Frederick S.

    AU - Akingbemi, Benson T.

    AU - Belcher, Scott M.

    AU - Crain, David A.

    AU - Crews, David

    AU - Guidice, Linda C.

    AU - Hunt, Patricia A.

    AU - Leranth, Csaba

    AU - Myers, John Peterson

    AU - Nadal, Angel

    AU - Olea, Nicholas

    AU - Padmanabhan, Vasantha

    AU - Rosenfeld, Cheryl S.

    AU - Schneyer, Alan

    AU - Schoenfelder, Gilbert

    AU - Sonnenschein, Carlos

    AU - Soto, Ana M.

    AU - Stahlhut, Richard W.

    AU - Swan, Shanna H.

    AU - Vandenberg, Laura N.

    AU - Wang, Hong Sheng

    AU - Watson, Cheryl S.

    AU - Welshons, Wade V.

    AU - Zoeller, Robert T.

    PY - 2010/2/17

    Y1 - 2010/2/17

    UR - http://www.scopus.com/inward/record.url?scp=77954075822&partnerID=8YFLogxK

    UR - http://www.scopus.com/inward/citedby.url?scp=77954075822&partnerID=8YFLogxK

    U2 - 10.1093/toxsci/kfq048

    DO - 10.1093/toxsci/kfq048

    M3 - Article

    VL - 115

    SP - 612

    EP - 613

    JO - Toxicological Sciences

    JF - Toxicological Sciences

    SN - 1096-6080

    IS - 2

    ER -