Flumazenil for the reversal of refractory benzodiazepine-induced shock

Wendy Coates; Timothy C. Evans; Dietrich Jehle; Fred Harchelroad; Marshal Isaacs

doi:10.3109/15563659109025752

Flumazenil for the reversal of refractory benzodiazepine-induced shock

Wendy Coates, Timothy C. Evans, Dietrich Jehle, Fred Harchelroad, Marshal Isaacs

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Benzodiazepines are known to cause central nervous system and centrally mediated cardiovascular depression. The benzodiazepine antagonist flumazenil has been shown to antagonize benzodiazepine-induced central nervous system depression. We report a case in which cardiovascular depression secondary to benzodiazepine use was reversed by this agent.

Original language	English (US)
Pages (from-to)	537-542
Number of pages	6
Journal	Clinical Toxicology
Volume	29
Issue number	4
DOIs	https://doi.org/10.3109/15563659109025752
State	Published - 1991
Externally published	Yes

Keywords

Benzodiazepine-induced shock
Flumazenil

ASJC Scopus subject areas

Toxicology

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10.3109/15563659109025752

Cite this

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title = "Flumazenil for the reversal of refractory benzodiazepine-induced shock",

abstract = "Benzodiazepines are known to cause central nervous system and centrally mediated cardiovascular depression. The benzodiazepine antagonist flumazenil has been shown to antagonize benzodiazepine-induced central nervous system depression. We report a case in which cardiovascular depression secondary to benzodiazepine use was reversed by this agent.",

keywords = "Benzodiazepine-induced shock, Flumazenil",

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year = "1991",

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T1 - Flumazenil for the reversal of refractory benzodiazepine-induced shock

AU - Coates, Wendy

AU - Evans, Timothy C.

AU - Jehle, Dietrich

AU - Harchelroad, Fred

AU - Isaacs, Marshal

PY - 1991

Y1 - 1991

N2 - Benzodiazepines are known to cause central nervous system and centrally mediated cardiovascular depression. The benzodiazepine antagonist flumazenil has been shown to antagonize benzodiazepine-induced central nervous system depression. We report a case in which cardiovascular depression secondary to benzodiazepine use was reversed by this agent.

AB - Benzodiazepines are known to cause central nervous system and centrally mediated cardiovascular depression. The benzodiazepine antagonist flumazenil has been shown to antagonize benzodiazepine-induced central nervous system depression. We report a case in which cardiovascular depression secondary to benzodiazepine use was reversed by this agent.

KW - Benzodiazepine-induced shock

KW - Flumazenil

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U2 - 10.3109/15563659109025752

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M3 - Article

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JO - Clinical Toxicology

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ER -

Flumazenil for the reversal of refractory benzodiazepine-induced shock

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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