Force-Regulated Spontaneous Conformational Changes of Integrins α₅β₁and α_Vβ₃

Keyphrases

• Conformational Change 100%
• Integrin 100%
• Energy Landscape 25%
• Hydrogen Bonds (H-bonds) 16%
• Protein-based 8%
• Cell Surface 8%
• Mechanical Force 8%
• Single Molecule 8%
• Cell Motility 8%
• Piconewton 8%
• Mechanosensitive 8%
• Mechanosensitivity 8%
• Ectodomain 8%
• Molecular Dynamics Simulation 8%
• Behavioral Activity 8%
• Extended Conformation 8%
• Conformational Transition 8%
• Biomaterials 8%
• Extracellular Environment 8%
• Design Principles 8%
• Nanomedicine 8%
• Cellular Mechanotransduction 8%
• Nanomachines 8%
• Intermediate State 8%
• Energy Barrier 8%
• HexA 8%
• Stable Intermediate 8%
• Change Process 8%
• State Energy 8%
• Nanosize 8%
• Single-particle Energy 8%
• Mechanosignaling 8%
• Small Step 8%
• Transition Time 8%
• Biomechanical Approach 8%
• Energy Well 8%
• Intermediate Energy 8%
• Canonical Energy 8%
• Bistability 8%
• Activity Structure 8%

Biochemistry, Genetics and Molecular Biology

• Conformational Change 100%
• Integrin 100%
• Energy Landscape 25%
• Hydrogen Bond 16%
• Conformation 16%
• Chlordiazepoxide 16%
• Cell Motility 8%
• Cell Migration 8%
• Ectodomain 8%
• Mechanotransduction 8%
• Mechanosensitivity 8%