Fourier transform infrared spectroscopy demonstrates the reactivity of the protonated carboxyl group of the acid salt of calcium bilirubinate

R. D. Soloway; J. G. Wu; D. F. Xu; Y. F. Zhang; D. K. Martini; N. K. Hong; R. S. Crowther

doi:10.1117/12.969451

Fourier transform infrared spectroscopy demonstrates the reactivity of the protonated carboxyl group of the acid salt of calcium bilirubinate

R. D. Soloway, J. G. Wu, D. F. Xu, Y. F. Zhang, D. K. Martini, N. K. Hong, R. S. Crowther

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Calcium bilirubinate is a major salt in pigment gallstones. Bilirubin IX (H2BR) is a tetrapyrrole with 1 propionic acid side chain on both the B and C rings. A striking feature is the strong intramolecular hydrogen bonding of both carboxyl groups as determined by x-ray diffraction. This greatly reduces aqueous solubility. Much less is known about the structure of the salts of calcium bilirubinate since single crystals have not been formed. One or both carboxyl groups of bilirubin may coordinate with calcium in stone, forming the acid or neutral salt.

Original language	English (US)
Pages (from-to)	262-263
Number of pages	2
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	1145
DOIs	https://doi.org/10.1117/12.969451
State	Published - Dec 1 1989
Externally published	Yes

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Computer Science Applications
Applied Mathematics
Electrical and Electronic Engineering

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Soloway, R. D., Wu, J. G., Xu, D. F., Zhang, Y. F., Martini, D. K., Hong, N. K., & Crowther, R. S. (1989). Fourier transform infrared spectroscopy demonstrates the reactivity of the protonated carboxyl group of the acid salt of calcium bilirubinate. Proceedings of SPIE - The International Society for Optical Engineering, 1145, 262-263. https://doi.org/10.1117/12.969451

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abstract = "Calcium bilirubinate is a major salt in pigment gallstones. Bilirubin IX (H2BR) is a tetrapyrrole with 1 propionic acid side chain on both the B and C rings. A striking feature is the strong intramolecular hydrogen bonding of both carboxyl groups as determined by x-ray diffraction. This greatly reduces aqueous solubility. Much less is known about the structure of the salts of calcium bilirubinate since single crystals have not been formed. One or both carboxyl groups of bilirubin may coordinate with calcium in stone, forming the acid or neutral salt.",

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T1 - Fourier transform infrared spectroscopy demonstrates the reactivity of the protonated carboxyl group of the acid salt of calcium bilirubinate

AU - Soloway, R. D.

AU - Wu, J. G.

AU - Xu, D. F.

AU - Zhang, Y. F.

AU - Martini, D. K.

AU - Hong, N. K.

AU - Crowther, R. S.

PY - 1989/12/1

Y1 - 1989/12/1

N2 - Calcium bilirubinate is a major salt in pigment gallstones. Bilirubin IX (H2BR) is a tetrapyrrole with 1 propionic acid side chain on both the B and C rings. A striking feature is the strong intramolecular hydrogen bonding of both carboxyl groups as determined by x-ray diffraction. This greatly reduces aqueous solubility. Much less is known about the structure of the salts of calcium bilirubinate since single crystals have not been formed. One or both carboxyl groups of bilirubin may coordinate with calcium in stone, forming the acid or neutral salt.

AB - Calcium bilirubinate is a major salt in pigment gallstones. Bilirubin IX (H2BR) is a tetrapyrrole with 1 propionic acid side chain on both the B and C rings. A striking feature is the strong intramolecular hydrogen bonding of both carboxyl groups as determined by x-ray diffraction. This greatly reduces aqueous solubility. Much less is known about the structure of the salts of calcium bilirubinate since single crystals have not been formed. One or both carboxyl groups of bilirubin may coordinate with calcium in stone, forming the acid or neutral salt.

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Fourier transform infrared spectroscopy demonstrates the reactivity of the protonated carboxyl group of the acid salt of calcium bilirubinate

Abstract

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