Foxp3+ regulatory T cells in antiretroviral-naive HIV patients

Martin Montes, Dorothy E. Lewis, Cesar Sanchez, Diego Lopez De Castilla, Edward A. Graviss, Carlos Seas, Eduardo Gotuzzo, A. Clinton White

Research output: Contribution to journalArticle

55 Scopus citations

Abstract

We characterized regulatory T cells from antiretroviral-naive HIV patients by flow cytometry. The proportion of CD4 cells positive for CD25 and Foxp3 was increased, mainly in those with CD4 cell counts less than 200 cells/μl. The total number of Foxp3-positive cells correlated with the CD4 cell count. Further studies are needed on whether Foxp3-positive cell numbers or function explain the susceptibility to autoimmune and inflammatory diseases seen in some patients with advanced HIV.

Original languageEnglish (US)
Pages (from-to)1669-1671
Number of pages3
JournalAIDS
Volume20
Issue number12
DOIs
StatePublished - Aug 1 2006

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ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Infectious Diseases

Cite this

Montes, M., Lewis, D. E., Sanchez, C., De Castilla, D. L., Graviss, E. A., Seas, C., Gotuzzo, E., & White, A. C. (2006). Foxp3+ regulatory T cells in antiretroviral-naive HIV patients. AIDS, 20(12), 1669-1671. https://doi.org/10.1097/01.aids.0000238415.98194.38