Foxp3+ regulatory T cells in antiretroviral-naive HIV patients

Martin Montes, Dorothy E. Lewis, Cesar Sanchez, Diego Lopez De Castilla, Edward A. Graviss, Carlos Seas, Eduardo Gotuzzo, A. Clinton White

Research output: Contribution to journalArticle

55 Citations (Scopus)

Abstract

We characterized regulatory T cells from antiretroviral-naive HIV patients by flow cytometry. The proportion of CD4 cells positive for CD25 and Foxp3 was increased, mainly in those with CD4 cell counts less than 200 cells/μl. The total number of Foxp3-positive cells correlated with the CD4 cell count. Further studies are needed on whether Foxp3-positive cell numbers or function explain the susceptibility to autoimmune and inflammatory diseases seen in some patients with advanced HIV.

Original languageEnglish (US)
Pages (from-to)1669-1671
Number of pages3
JournalAIDS
Volume20
Issue number12
DOIs
StatePublished - Aug 2006
Externally publishedYes

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Regulatory T-Lymphocytes
HIV
CD4 Lymphocyte Count
Autoimmune Diseases
Flow Cytometry
Cell Count

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

Cite this

Montes, M., Lewis, D. E., Sanchez, C., De Castilla, D. L., Graviss, E. A., Seas, C., ... White, A. C. (2006). Foxp3+ regulatory T cells in antiretroviral-naive HIV patients. AIDS, 20(12), 1669-1671. https://doi.org/10.1097/01.aids.0000238415.98194.38

Foxp3+ regulatory T cells in antiretroviral-naive HIV patients. / Montes, Martin; Lewis, Dorothy E.; Sanchez, Cesar; De Castilla, Diego Lopez; Graviss, Edward A.; Seas, Carlos; Gotuzzo, Eduardo; White, A. Clinton.

In: AIDS, Vol. 20, No. 12, 08.2006, p. 1669-1671.

Research output: Contribution to journalArticle

Montes, M, Lewis, DE, Sanchez, C, De Castilla, DL, Graviss, EA, Seas, C, Gotuzzo, E & White, AC 2006, 'Foxp3+ regulatory T cells in antiretroviral-naive HIV patients', AIDS, vol. 20, no. 12, pp. 1669-1671. https://doi.org/10.1097/01.aids.0000238415.98194.38
Montes M, Lewis DE, Sanchez C, De Castilla DL, Graviss EA, Seas C et al. Foxp3+ regulatory T cells in antiretroviral-naive HIV patients. AIDS. 2006 Aug;20(12):1669-1671. https://doi.org/10.1097/01.aids.0000238415.98194.38
Montes, Martin ; Lewis, Dorothy E. ; Sanchez, Cesar ; De Castilla, Diego Lopez ; Graviss, Edward A. ; Seas, Carlos ; Gotuzzo, Eduardo ; White, A. Clinton. / Foxp3+ regulatory T cells in antiretroviral-naive HIV patients. In: AIDS. 2006 ; Vol. 20, No. 12. pp. 1669-1671.
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