Abstract
We characterized regulatory T cells from antiretroviral-naive HIV patients by flow cytometry. The proportion of CD4 cells positive for CD25 and Foxp3 was increased, mainly in those with CD4 cell counts less than 200 cells/μl. The total number of Foxp3-positive cells correlated with the CD4 cell count. Further studies are needed on whether Foxp3-positive cell numbers or function explain the susceptibility to autoimmune and inflammatory diseases seen in some patients with advanced HIV.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1669-1671 |
| Number of pages | 3 |
| Journal | AIDS |
| Volume | 20 |
| Issue number | 12 |
| DOIs | |
| State | Published - Aug 2006 |
| Externally published | Yes |
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology
- Infectious Diseases