Fractional flow reserve at 2013: An update

S. Sattur, A. Mathur, S. Acharji, A. H. Waller, Sendil Prasad, M. Singh, W. Rudzinski, E. Kaluski

Research output: Contribution to journalReview article

Abstract

Fractional flow reserve (FFR) has become an extremely valuable tool for assessing the hemodynamic significance of intermediate coronary lesions in patients with stable coronary syndromes. This manuscript delineates the current data supporting FFR use to guide cardiovascular interventions in comparison to other invasive and non-invasive modalities. The correlation between FFR, symptom severity and likelihood of future major cardiovascular events are critically examined in view of the FAME-2 study results. The authors delineate the scientific gaps, potential pitfalls and misconceptions related to FFR with regards to current and emerging indications. Described are the most important developments related to FFR in 2012: instantaneous wave free ratio and non-invasive CT angiography based FFR. The manuscript proposes areas of future research to enhance the scientific data supporting current FFR clinical algorithms and strategies.

Original languageEnglish (US)
Pages (from-to)21-32
Number of pages12
JournalMinerva Cardioangiologica
Volume61
Issue number1
StatePublished - Feb 2013
Externally publishedYes

Fingerprint

Manuscripts
Hemodynamics
Computed Tomography Angiography

Keywords

  • Computed tomography
  • Coronary artery disease
  • Fractional flow reserve, myocardial

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Sattur, S., Mathur, A., Acharji, S., Waller, A. H., Prasad, S., Singh, M., ... Kaluski, E. (2013). Fractional flow reserve at 2013: An update. Minerva Cardioangiologica, 61(1), 21-32.

Fractional flow reserve at 2013 : An update. / Sattur, S.; Mathur, A.; Acharji, S.; Waller, A. H.; Prasad, Sendil; Singh, M.; Rudzinski, W.; Kaluski, E.

In: Minerva Cardioangiologica, Vol. 61, No. 1, 02.2013, p. 21-32.

Research output: Contribution to journalReview article

Sattur, S, Mathur, A, Acharji, S, Waller, AH, Prasad, S, Singh, M, Rudzinski, W & Kaluski, E 2013, 'Fractional flow reserve at 2013: An update', Minerva Cardioangiologica, vol. 61, no. 1, pp. 21-32.
Sattur S, Mathur A, Acharji S, Waller AH, Prasad S, Singh M et al. Fractional flow reserve at 2013: An update. Minerva Cardioangiologica. 2013 Feb;61(1):21-32.
Sattur, S. ; Mathur, A. ; Acharji, S. ; Waller, A. H. ; Prasad, Sendil ; Singh, M. ; Rudzinski, W. ; Kaluski, E. / Fractional flow reserve at 2013 : An update. In: Minerva Cardioangiologica. 2013 ; Vol. 61, No. 1. pp. 21-32.
@article{920c62a8c42a495e8179e325ac3d9db3,
title = "Fractional flow reserve at 2013: An update",
abstract = "Fractional flow reserve (FFR) has become an extremely valuable tool for assessing the hemodynamic significance of intermediate coronary lesions in patients with stable coronary syndromes. This manuscript delineates the current data supporting FFR use to guide cardiovascular interventions in comparison to other invasive and non-invasive modalities. The correlation between FFR, symptom severity and likelihood of future major cardiovascular events are critically examined in view of the FAME-2 study results. The authors delineate the scientific gaps, potential pitfalls and misconceptions related to FFR with regards to current and emerging indications. Described are the most important developments related to FFR in 2012: instantaneous wave free ratio and non-invasive CT angiography based FFR. The manuscript proposes areas of future research to enhance the scientific data supporting current FFR clinical algorithms and strategies.",
keywords = "Computed tomography, Coronary artery disease, Fractional flow reserve, myocardial",
author = "S. Sattur and A. Mathur and S. Acharji and Waller, {A. H.} and Sendil Prasad and M. Singh and W. Rudzinski and E. Kaluski",
year = "2013",
month = "2",
language = "English (US)",
volume = "61",
pages = "21--32",
journal = "Minerva Cardioangiologica",
issn = "0026-4725",
publisher = "Edizioni Minerva Medica S.p.A.",
number = "1",

}

TY - JOUR

T1 - Fractional flow reserve at 2013

T2 - An update

AU - Sattur, S.

AU - Mathur, A.

AU - Acharji, S.

AU - Waller, A. H.

AU - Prasad, Sendil

AU - Singh, M.

AU - Rudzinski, W.

AU - Kaluski, E.

PY - 2013/2

Y1 - 2013/2

N2 - Fractional flow reserve (FFR) has become an extremely valuable tool for assessing the hemodynamic significance of intermediate coronary lesions in patients with stable coronary syndromes. This manuscript delineates the current data supporting FFR use to guide cardiovascular interventions in comparison to other invasive and non-invasive modalities. The correlation between FFR, symptom severity and likelihood of future major cardiovascular events are critically examined in view of the FAME-2 study results. The authors delineate the scientific gaps, potential pitfalls and misconceptions related to FFR with regards to current and emerging indications. Described are the most important developments related to FFR in 2012: instantaneous wave free ratio and non-invasive CT angiography based FFR. The manuscript proposes areas of future research to enhance the scientific data supporting current FFR clinical algorithms and strategies.

AB - Fractional flow reserve (FFR) has become an extremely valuable tool for assessing the hemodynamic significance of intermediate coronary lesions in patients with stable coronary syndromes. This manuscript delineates the current data supporting FFR use to guide cardiovascular interventions in comparison to other invasive and non-invasive modalities. The correlation between FFR, symptom severity and likelihood of future major cardiovascular events are critically examined in view of the FAME-2 study results. The authors delineate the scientific gaps, potential pitfalls and misconceptions related to FFR with regards to current and emerging indications. Described are the most important developments related to FFR in 2012: instantaneous wave free ratio and non-invasive CT angiography based FFR. The manuscript proposes areas of future research to enhance the scientific data supporting current FFR clinical algorithms and strategies.

KW - Computed tomography

KW - Coronary artery disease

KW - Fractional flow reserve, myocardial

UR - http://www.scopus.com/inward/record.url?scp=84876257839&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84876257839&partnerID=8YFLogxK

M3 - Review article

C2 - 23381377

AN - SCOPUS:84876257839

VL - 61

SP - 21

EP - 32

JO - Minerva Cardioangiologica

JF - Minerva Cardioangiologica

SN - 0026-4725

IS - 1

ER -