François Magendie (1783-1855) and his contributions to the foundations of neuroscience and neurosurgery.

R. Shane Tubbs, Marios Loukas, Mohammadali Mohajel Shoja, Ghaffar Shokouhi, W. Jerry Oakes

Research output: Contribution to journalArticlepeer-review

24 Scopus citations


François Magendie lived during a tumultuous period in French history. Although this early medical pioneer made significant contributions to the fields of neuroanatomy, physiology, and pharmacology, little information is found in the non-French literature regarding this significant person in history. Based on this review, one could also consider this trained surgeon as an early pioneer of neurosurgery. For example, he is known to have used Galvanic current to treat various neuralgias, described a technique for extracting cerebrospinal fluid and quantitated and described its characteristics in normal and pathological specimens, and elucidated the functions of the the cranial nerves using vivisection. Additionally, he accurately described the functions of the dorsal and ventral rootlets using vivisection, and realized that the exposed meninges were susceptible to painful stimuli. Our current knowledge is based on the early contributions of scientists such as François Magendie.

Original languageEnglish (US)
Pages (from-to)1038-1042
Number of pages5
JournalJournal of neurosurgery
Issue number5
StatePublished - Jan 1 2008
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology


Dive into the research topics of 'François Magendie (1783-1855) and his contributions to the foundations of neuroscience and neurosurgery.'. Together they form a unique fingerprint.

Cite this