Free electron laser ablation of urinary calculi

An experimental study

Kin Foong Chan, Bernard Choi, Gracie Vargas, Daniel X. Hammer, Brian Sorg, T. Joshua Pfefer, Joel M H Teichman, Ashley J. Welch, E. Duco Jansen

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Infrared laser ablation of urinary calculi was investigated as a function of wavelength to determine the relation of ablation threshold fluences, ablation depths, and optical absorption. A simple photothermal ablation model was employed to examine this relationship. Human urinary calculi composed of > 95% uric acid, > 95% cystine, > 95% calcium oxalate monohydrate (COM), and > 90% magnesium ammonium phosphate hexahydrate (MAPH) were used. Various wavelengths between 2.1 and 6.5 μm were selected to perform threshold fluence and ablation depth measurements. The laser source for this study was the tunable pulsed infrared free electron laser (FEL) at Vanderbilt University. Experimental results indicated a correlation of threshold fluence and ablation depth to the optical absorption properties of the calculi. When calculus optical absorption increased, the threshold fluences decreased. Although the ablation depths increased with calculus optical absorption, results indicated that in certain calculi the ablation depth was affected by optical attenuation through the ablation plume. These observations were in agreement with the photothermal ablation model, but fractures in striated calculi at higher optical absorptions, indicated the contribution of a photomechanical mechanism. Threshold fluences and ablation depths are a function of the wavelength dependent absorption properties of the calculi. These observations suggest that the 3-μm and 6-μm absorption bands are optimal for ablation or fragmentation of urinary calculus.

Original languageEnglish (US)
Pages (from-to)1022-1033
Number of pages12
JournalIEEE Journal on Selected Topics in Quantum Electronics
Volume7
Issue number6
DOIs
StatePublished - Nov 2001
Externally publishedYes

Fingerprint

calculi
Free electron lasers
Laser ablation
Ablation
free electron lasers
laser ablation
ablation
calculus
Light absorption
fluence
optical absorption
thresholds
Infrared lasers
infrared lasers
Wavelength
wavelengths
Cystines
ammonium phosphates
uric acid
depth measurement

Keywords

  • Absorption
  • Fluence
  • Fragmentation
  • Infrared
  • Kidney stone
  • Lithotripsy
  • Radiant exposure
  • Thermal
  • Urology

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Atomic and Molecular Physics, and Optics

Cite this

Free electron laser ablation of urinary calculi : An experimental study. / Chan, Kin Foong; Choi, Bernard; Vargas, Gracie; Hammer, Daniel X.; Sorg, Brian; Pfefer, T. Joshua; Teichman, Joel M H; Welch, Ashley J.; Jansen, E. Duco.

In: IEEE Journal on Selected Topics in Quantum Electronics, Vol. 7, No. 6, 11.2001, p. 1022-1033.

Research output: Contribution to journalArticle

Chan, KF, Choi, B, Vargas, G, Hammer, DX, Sorg, B, Pfefer, TJ, Teichman, JMH, Welch, AJ & Jansen, ED 2001, 'Free electron laser ablation of urinary calculi: An experimental study', IEEE Journal on Selected Topics in Quantum Electronics, vol. 7, no. 6, pp. 1022-1033. https://doi.org/10.1109/2944.983308
Chan, Kin Foong ; Choi, Bernard ; Vargas, Gracie ; Hammer, Daniel X. ; Sorg, Brian ; Pfefer, T. Joshua ; Teichman, Joel M H ; Welch, Ashley J. ; Jansen, E. Duco. / Free electron laser ablation of urinary calculi : An experimental study. In: IEEE Journal on Selected Topics in Quantum Electronics. 2001 ; Vol. 7, No. 6. pp. 1022-1033.
@article{263f716da36d48ac850042c06f1dc9b7,
title = "Free electron laser ablation of urinary calculi: An experimental study",
abstract = "Infrared laser ablation of urinary calculi was investigated as a function of wavelength to determine the relation of ablation threshold fluences, ablation depths, and optical absorption. A simple photothermal ablation model was employed to examine this relationship. Human urinary calculi composed of > 95{\%} uric acid, > 95{\%} cystine, > 95{\%} calcium oxalate monohydrate (COM), and > 90{\%} magnesium ammonium phosphate hexahydrate (MAPH) were used. Various wavelengths between 2.1 and 6.5 μm were selected to perform threshold fluence and ablation depth measurements. The laser source for this study was the tunable pulsed infrared free electron laser (FEL) at Vanderbilt University. Experimental results indicated a correlation of threshold fluence and ablation depth to the optical absorption properties of the calculi. When calculus optical absorption increased, the threshold fluences decreased. Although the ablation depths increased with calculus optical absorption, results indicated that in certain calculi the ablation depth was affected by optical attenuation through the ablation plume. These observations were in agreement with the photothermal ablation model, but fractures in striated calculi at higher optical absorptions, indicated the contribution of a photomechanical mechanism. Threshold fluences and ablation depths are a function of the wavelength dependent absorption properties of the calculi. These observations suggest that the 3-μm and 6-μm absorption bands are optimal for ablation or fragmentation of urinary calculus.",
keywords = "Absorption, Fluence, Fragmentation, Infrared, Kidney stone, Lithotripsy, Radiant exposure, Thermal, Urology",
author = "Chan, {Kin Foong} and Bernard Choi and Gracie Vargas and Hammer, {Daniel X.} and Brian Sorg and Pfefer, {T. Joshua} and Teichman, {Joel M H} and Welch, {Ashley J.} and Jansen, {E. Duco}",
year = "2001",
month = "11",
doi = "10.1109/2944.983308",
language = "English (US)",
volume = "7",
pages = "1022--1033",
journal = "IEEE Journal of Selected Topics in Quantum Electronics",
issn = "1077-260X",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
number = "6",

}

TY - JOUR

T1 - Free electron laser ablation of urinary calculi

T2 - An experimental study

AU - Chan, Kin Foong

AU - Choi, Bernard

AU - Vargas, Gracie

AU - Hammer, Daniel X.

AU - Sorg, Brian

AU - Pfefer, T. Joshua

AU - Teichman, Joel M H

AU - Welch, Ashley J.

AU - Jansen, E. Duco

PY - 2001/11

Y1 - 2001/11

N2 - Infrared laser ablation of urinary calculi was investigated as a function of wavelength to determine the relation of ablation threshold fluences, ablation depths, and optical absorption. A simple photothermal ablation model was employed to examine this relationship. Human urinary calculi composed of > 95% uric acid, > 95% cystine, > 95% calcium oxalate monohydrate (COM), and > 90% magnesium ammonium phosphate hexahydrate (MAPH) were used. Various wavelengths between 2.1 and 6.5 μm were selected to perform threshold fluence and ablation depth measurements. The laser source for this study was the tunable pulsed infrared free electron laser (FEL) at Vanderbilt University. Experimental results indicated a correlation of threshold fluence and ablation depth to the optical absorption properties of the calculi. When calculus optical absorption increased, the threshold fluences decreased. Although the ablation depths increased with calculus optical absorption, results indicated that in certain calculi the ablation depth was affected by optical attenuation through the ablation plume. These observations were in agreement with the photothermal ablation model, but fractures in striated calculi at higher optical absorptions, indicated the contribution of a photomechanical mechanism. Threshold fluences and ablation depths are a function of the wavelength dependent absorption properties of the calculi. These observations suggest that the 3-μm and 6-μm absorption bands are optimal for ablation or fragmentation of urinary calculus.

AB - Infrared laser ablation of urinary calculi was investigated as a function of wavelength to determine the relation of ablation threshold fluences, ablation depths, and optical absorption. A simple photothermal ablation model was employed to examine this relationship. Human urinary calculi composed of > 95% uric acid, > 95% cystine, > 95% calcium oxalate monohydrate (COM), and > 90% magnesium ammonium phosphate hexahydrate (MAPH) were used. Various wavelengths between 2.1 and 6.5 μm were selected to perform threshold fluence and ablation depth measurements. The laser source for this study was the tunable pulsed infrared free electron laser (FEL) at Vanderbilt University. Experimental results indicated a correlation of threshold fluence and ablation depth to the optical absorption properties of the calculi. When calculus optical absorption increased, the threshold fluences decreased. Although the ablation depths increased with calculus optical absorption, results indicated that in certain calculi the ablation depth was affected by optical attenuation through the ablation plume. These observations were in agreement with the photothermal ablation model, but fractures in striated calculi at higher optical absorptions, indicated the contribution of a photomechanical mechanism. Threshold fluences and ablation depths are a function of the wavelength dependent absorption properties of the calculi. These observations suggest that the 3-μm and 6-μm absorption bands are optimal for ablation or fragmentation of urinary calculus.

KW - Absorption

KW - Fluence

KW - Fragmentation

KW - Infrared

KW - Kidney stone

KW - Lithotripsy

KW - Radiant exposure

KW - Thermal

KW - Urology

UR - http://www.scopus.com/inward/record.url?scp=0035521267&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035521267&partnerID=8YFLogxK

U2 - 10.1109/2944.983308

DO - 10.1109/2944.983308

M3 - Article

VL - 7

SP - 1022

EP - 1033

JO - IEEE Journal of Selected Topics in Quantum Electronics

JF - IEEE Journal of Selected Topics in Quantum Electronics

SN - 1077-260X

IS - 6

ER -