Frostbite: Methods to minimize tissue loss

R. L. McCauley, J. P. Heggers, M. C. Robson

Research output: Contribution to journalArticlepeer-review

52 Scopus citations


If frostbite is to be treated successfully, direct and indirect effects of injury must be understood. Rapid rewarming helps to preserve tissue by limiting the amount of direct cellular injury. Selective management of blisters helps protect the subdermal plexus, and application of Aloe vera cream (eg, Dermaide Aloe Cream) combats the local vasoconstrictive effects of thromboxane. Oral administration of ibuprofen decreases systemic levels of thromboxane.

Original languageEnglish (US)
Pages (from-to)67-68+73-74+76-77
JournalPostgraduate medicine
Issue number8
StatePublished - 1990

ASJC Scopus subject areas

  • General Medicine


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