Functional visualization of viral molecular motor by hydrogen-deuterium exchange reveals transient states

Keyphrases

• Viral 100%
• Molecular Motor 100%
• Hydrogen-deuterium Exchange 100%
• Transient State 100%
• Hexameric Helicase 66%
• Cooperative Unit 66%
• Double-stranded RNA 33%
• High-resolution 33%
• Conformational Change 33%
• Molecular Machines 33%
• Helix 33%
• Viral Packaging 33%
• Bacteriophage 33%
• Hexameric Ring 33%
• Transition State 33%
• Time-resolved 33%
• Conformational Dynamics 33%
• Chemical Energy 33%
• Deuterium Labeling 33%
• Liquid Chromatography-high Resolution Mass Spectrometry (LC-HRMS) 33%
• Packaging Motor 33%
• RNA Binding 33%
• Mechanical Work 33%
• ATP Binding Site 33%
• Loading Mechanism 33%
• Structure Model 33%
• Exchange Kinetics 33%
• Structural Snapshots 33%
• Spectroscopic Observations 33%

Biochemistry, Genetics and Molecular Biology

• Molecular Motor 100%
• Motor Protein 100%
• Hydrogen-Deuterium Exchange 100%
• Helicase 66%
• Dynamics 33%
• Adenosine Triphosphate 33%
• Double-Stranded RNA 33%
• RNA 33%
• Conformational Change 33%
• Binding Site 33%
• RNA Binding 33%
• Resolution (Mass Spectrometry) 33%
• Bacteriophage 33%