Future directions in regional treatment strategies for melanoma and sarcoma

G. M. Beasley, M. I. Ross, D. S. Tyler

Research output: Contribution to journalArticle

18 Scopus citations

Abstract

Hyperthermic isolated limb perfusion (HILP) with melphalan and more recently isolated limb infusion (ILI) with melphalan +/- dactinomycin are common treatment modalities for both in-transit melanoma of the extremity and advanced extremity sarcoma. In order to further optimize treatment, future research should focus on selection of appropriate patients, verification of a technique that produces consistent results while maintaining acceptable toxicity, and development of novel strategies and agents. Development of these novel agents and strategies has potential to not only improve the efficacy of regional chemotherapy but may also help guide future strategies for systemic treatment.

Original languageEnglish (US)
Pages (from-to)301-309
Number of pages9
JournalInternational Journal of Hyperthermia
Volume24
Issue number3
DOIs
StatePublished - May 1 2008
Externally publishedYes

Keywords

  • Melanoma
  • Regional chemotherapy

ASJC Scopus subject areas

  • Physiology
  • Physiology (medical)
  • Cancer Research

Fingerprint Dive into the research topics of 'Future directions in regional treatment strategies for melanoma and sarcoma'. Together they form a unique fingerprint.

  • Cite this