Future Therapies in Burn Resuscitation

Erica I. Hodgman, Madhu Subramanian, Brett D. Arnoldo, Herb A. Phelan, Steven E. Wolf

Research output: Contribution to journalReview articlepeer-review

14 Scopus citations


Since the 1940s, the resuscitation of burn patients has evolved with dramatic improvements in mortality. The most significant achievement remains the creation and adoption of formulae to calculate estimated fluid requirements to guide resuscitation. Modalities to attenuate the hypermetabolic phase of injury include pharmacologic agents, early enteral nutrition, and the aggressive approach of early excision of large injuries. Recent investigations into the genomic response to severe burns and the application of computer-based decision support tools will likely guide future resuscitation, with the goal of further reducing mortality and morbidity, and improving functional and quality of life outcomes.

Original languageEnglish (US)
Pages (from-to)611-619
Number of pages9
JournalCritical Care Clinics
Issue number4
StatePublished - Oct 1 2016
Externally publishedYes


  • Burns
  • Fluid creep
  • Fluid resuscitation
  • Monitoring

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine


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