GABAergic vesicle-containing dendrites and spines: A critical element in processing sensory input in the monkey dorsal horn

Susan M. Carlton, Elizabeth S. Hayes

    Research output: Contribution to journalArticle

    25 Citations (Scopus)

    Abstract

    Antibodies directed against γ-aminobutyric acid (GABA) were used to immunostain monkey lumbar spinal cord. In laminae I and II, ultrastructural analysis demonstrated GABA-immunoreactive (-IR) vesicle-containing dendrites as well as the more commonly emphasized immunoreactive cell bodies and terminals. Spines were a consistent feature of these dendrites, and some of the spines contained synaptic vesicles. GABA-IR dendrites were observed postsynaptic to large glomerular-type terminals, small-diameter axon terminals and other vesicle-containing dendrites. They were presynaptic to dendritic shafts and spines. These data suggest that GABA-IR dendrites and dendritic spines may play an important role not only as receptive elements but also provide a means for transferring information from neuron to neuron.

    Original languageEnglish (US)
    Pages (from-to)40-42
    Number of pages3
    JournalNeuroscience Letters
    Volume121
    Issue number1-2
    DOIs
    StatePublished - Jan 2 1991

    Fingerprint

    Dendrites
    Haplorhini
    Spine
    gamma-Aminobutyric Acid
    Dendritic Spines
    Spinal Cord
    Substantia Gelatinosa
    Aminobutyrates
    Neurons
    Synaptic Vesicles
    Presynaptic Terminals
    Spinal Cord Dorsal Horn
    Antibodies

    Keywords

    • Dendritic spine
    • Primate
    • Spinal cord
    • Vesicle-containing dendrite
    • γ-Aminobutyric acid

    ASJC Scopus subject areas

    • Neuroscience(all)

    Cite this

    GABAergic vesicle-containing dendrites and spines : A critical element in processing sensory input in the monkey dorsal horn. / Carlton, Susan M.; Hayes, Elizabeth S.

    In: Neuroscience Letters, Vol. 121, No. 1-2, 02.01.1991, p. 40-42.

    Research output: Contribution to journalArticle

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