Gamma globulin components of bovine colostrum and dry secretion were compared with their counterparts in serum by means of immunoelectrophoresis, anion exchange chromatography, and double-diffusion antigenic analysis. Although comparable components appeared immunochemically and physicochemically similar no matter where they originated, the proportional amount of each component varied greatly according to the character of the secretion. Thus, electrophoretically fast and slow 7S gamma globulin components were found to selectively accumulate in dry secretion relative to other serum proteins. Colostrum formation involved the same discrimination relative to other serum proteins and also a virtually complete discrimination against slow 7S gamma globulin in favor of a fast component. Bovine gamma-1M and gamma-1A globulins were found in lacteal secretions.
ASJC Scopus subject areas
- Molecular Biology