Gamma globulins of bovine lacteal secretions

Frederick A. Murphy; Ole Aalund; John W. Osebold; Edward J. Carroll

doi:10.1016/0003-9861(64)90380-7

Gamma globulins of bovine lacteal secretions

Frederick A. Murphy
, Ole Aalund
, John W. Osebold
, Edward J. Carroll

Research output: Contribution to journal › Article › peer-review

35 Scopus citations

Abstract

Gamma globulin components of bovine colostrum and dry secretion were compared with their counterparts in serum by means of immunoelectrophoresis, anion exchange chromatography, and double-diffusion antigenic analysis. Although comparable components appeared immunochemically and physicochemically similar no matter where they originated, the proportional amount of each component varied greatly according to the character of the secretion. Thus, electrophoretically fast and slow 7S gamma globulin components were found to selectively accumulate in dry secretion relative to other serum proteins. Colostrum formation involved the same discrimination relative to other serum proteins and also a virtually complete discrimination against slow 7S gamma globulin in favor of a fast component. Bovine gamma-1M and gamma-1A globulins were found in lacteal secretions.

Original language	English (US)
Pages (from-to)	230-239
Number of pages	10
Journal	Archives of Biochemistry and Biophysics
Volume	108
Issue number	2
DOIs	https://doi.org/10.1016/0003-9861(64)90380-7
State	Published - Nov 1964
Externally published	Yes

ASJC Scopus subject areas

Biophysics
Biochemistry
Molecular Biology

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10.1016/0003-9861(64)90380-7

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title = "Gamma globulins of bovine lacteal secretions",

abstract = "Gamma globulin components of bovine colostrum and dry secretion were compared with their counterparts in serum by means of immunoelectrophoresis, anion exchange chromatography, and double-diffusion antigenic analysis. Although comparable components appeared immunochemically and physicochemically similar no matter where they originated, the proportional amount of each component varied greatly according to the character of the secretion. Thus, electrophoretically fast and slow 7S gamma globulin components were found to selectively accumulate in dry secretion relative to other serum proteins. Colostrum formation involved the same discrimination relative to other serum proteins and also a virtually complete discrimination against slow 7S gamma globulin in favor of a fast component. Bovine gamma-1M and gamma-1A globulins were found in lacteal secretions.",

author = "Murphy, \{Frederick A.\} and Ole Aalund and Osebold, \{John W.\} and Carroll, \{Edward J.\}",

year = "1964",

month = nov,

doi = "10.1016/0003-9861(64)90380-7",

language = "English (US)",

volume = "108",

pages = "230--239",

journal = "Archives of Biochemistry and Biophysics",

issn = "0003-9861",

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number = "2",

}

TY - JOUR

T1 - Gamma globulins of bovine lacteal secretions

AU - Murphy, Frederick A.

AU - Aalund, Ole

AU - Osebold, John W.

AU - Carroll, Edward J.

PY - 1964/11

Y1 - 1964/11

N2 - Gamma globulin components of bovine colostrum and dry secretion were compared with their counterparts in serum by means of immunoelectrophoresis, anion exchange chromatography, and double-diffusion antigenic analysis. Although comparable components appeared immunochemically and physicochemically similar no matter where they originated, the proportional amount of each component varied greatly according to the character of the secretion. Thus, electrophoretically fast and slow 7S gamma globulin components were found to selectively accumulate in dry secretion relative to other serum proteins. Colostrum formation involved the same discrimination relative to other serum proteins and also a virtually complete discrimination against slow 7S gamma globulin in favor of a fast component. Bovine gamma-1M and gamma-1A globulins were found in lacteal secretions.

AB - Gamma globulin components of bovine colostrum and dry secretion were compared with their counterparts in serum by means of immunoelectrophoresis, anion exchange chromatography, and double-diffusion antigenic analysis. Although comparable components appeared immunochemically and physicochemically similar no matter where they originated, the proportional amount of each component varied greatly according to the character of the secretion. Thus, electrophoretically fast and slow 7S gamma globulin components were found to selectively accumulate in dry secretion relative to other serum proteins. Colostrum formation involved the same discrimination relative to other serum proteins and also a virtually complete discrimination against slow 7S gamma globulin in favor of a fast component. Bovine gamma-1M and gamma-1A globulins were found in lacteal secretions.

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U2 - 10.1016/0003-9861(64)90380-7

DO - 10.1016/0003-9861(64)90380-7

M3 - Article

C2 - 14240572

AN - SCOPUS:0347632714

SN - 0003-9861

VL - 108

SP - 230

EP - 239

JO - Archives of Biochemistry and Biophysics

JF - Archives of Biochemistry and Biophysics

IS - 2

ER -

Gamma globulins of bovine lacteal secretions

Abstract

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