Gaseotransmitters: New frontiers for translational science

Csaba Szabo

    Research output: Contribution to journalReview article

    75 Scopus citations

    Abstract

    Translational research on endogenous gaseous mediators - nitric oxide, carbon monoxide, and hydrogen sulfide - has exploded over the past decade. Drugs that modulate either the gaseous mediators themselves or their related intracellular signaling pathways are already in use in the clinics, and still more are being tested in preclinical models and clinical trials. Discussed here are the chemical and pharmacological properties that present challenges for the translation of these potentially toxic molecules.

    Original languageEnglish (US)
    Article number59ps54
    JournalScience Translational Medicine
    Volume2
    Issue number59
    DOIs
    StatePublished - Nov 24 2010

    ASJC Scopus subject areas

    • Medicine(all)

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