Gastrinoma

Courtney Townsend, J. C. Thompson

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

The Zollinger-Ellison syndrome with its main symptom of massive gastric hypersecretion presents problems with both the medical and surgical approaches to treatment. Successful medical treatment depends on a life-long commitment to rigid medication schedules requiring careful ongoing supervision and is subject to pitfalls of compliance, drug side effects, drug resistance, and complications of persistent tumor growth. Surgical therapy carries risks of operative mortality and complications. If a low operative mortality can be maintained and the nutritional results after total gastrectomy are good, then it is the authors' opinion that the permanent relief from dangers of hypersecretion afforded by total gastrectomy makes surgery a worthwhile approach. Based on our operative experience in 34 patients and interpretation of the experience of others, we believe that resection of all tumor that can be resected, combined with total gastrectomy, is safe and dependable. The results compare well with those of long-term medical management.

Original languageEnglish (US)
Pages (from-to)91-97
Number of pages7
JournalSeminars in Surgical Oncology
Volume6
Issue number2
DOIs
StatePublished - 1990

Fingerprint

Gastrinoma
Gastrectomy
Drug-Related Side Effects and Adverse Reactions
Zollinger-Ellison Syndrome
Mortality
Drug Resistance
Compliance
Neoplasms
Stomach
Appointments and Schedules
Therapeutics
Growth

ASJC Scopus subject areas

  • Surgery
  • Oncology

Cite this

Gastrinoma. / Townsend, Courtney; Thompson, J. C.

In: Seminars in Surgical Oncology, Vol. 6, No. 2, 1990, p. 91-97.

Research output: Contribution to journalArticle

Townsend, Courtney ; Thompson, J. C. / Gastrinoma. In: Seminars in Surgical Oncology. 1990 ; Vol. 6, No. 2. pp. 91-97.
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