Gastrointestinal motility

Some basic concepts

S. K. Sarna, M. F. Otterson

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

The spatial and temporal patterns of phasic contractions in the gastrointestinal tract are regulated by a complex interplay between the myogenic, neural and chemical control mechanisms. These contractions are largely responsible for the mixing and propulsive movements of the gut after a meal. In the fasted state, organized groups of contractions called cyclic motor activity and migrating motor complex keep the upper digestive tract clean of residual food and debris. In addition, the small intestine and the colon generate giant migrating contractions which are several-fold stronger than the postprandial phasic contractions and migrate uninterrupted over long distances. The giant contraction are effective in rapid propulsion. The upper small intestine and the antrum generate retrograde giant contractions that precede vomiting.

Original languageEnglish (US)
Pages (from-to)7-14
Number of pages8
JournalPharmacology
Volume36
Issue numberSUPPL. 1
StatePublished - 1988
Externally publishedYes

Fingerprint

Gastrointestinal Motility
Small Intestine
Gastrointestinal Tract
Migrating Myoelectric Complexes
Vomiting
Meals
Colon
Motor Activity
Food

ASJC Scopus subject areas

  • Pharmacology

Cite this

Sarna, S. K., & Otterson, M. F. (1988). Gastrointestinal motility: Some basic concepts. Pharmacology, 36(SUPPL. 1), 7-14.

Gastrointestinal motility : Some basic concepts. / Sarna, S. K.; Otterson, M. F.

In: Pharmacology, Vol. 36, No. SUPPL. 1, 1988, p. 7-14.

Research output: Contribution to journalArticle

Sarna, SK & Otterson, MF 1988, 'Gastrointestinal motility: Some basic concepts', Pharmacology, vol. 36, no. SUPPL. 1, pp. 7-14.
Sarna SK, Otterson MF. Gastrointestinal motility: Some basic concepts. Pharmacology. 1988;36(SUPPL. 1):7-14.
Sarna, S. K. ; Otterson, M. F. / Gastrointestinal motility : Some basic concepts. In: Pharmacology. 1988 ; Vol. 36, No. SUPPL. 1. pp. 7-14.
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