Gastrointestinal system, obesity, and body composition

Ann O. Scheimann, Phillip D.K. Lee, Kenneth J. Ellis

Research output: Chapter in Book/Report/Conference proceedingChapter

13 Scopus citations


Obesity or overweight is arguably the most obvious physical feature of PWS. Perhaps for this reason, more than 80% of the over 1,600 publications to date regarding PWS mention, discuss, and/or explore the topic of obesity. Despite this attention, the diagnosis, pathogenesis, optimal treatment, monitoring, and outcome of this condition in PWS remain undefi ned. In addition, the paradox of the underweight infant with PWS evolving into an overweight child and adult has led to considerable speculation regarding pathophysiology. In addition to the obvious physical feature of obesity/overweight and questions regarding optimal nutritional management, a variety of gastrointestinal (GI) disorders have been identifi ed in PWS, with frequencies similar to respiratory disorders. A description of the GI system and related disorders in PWS will start this chapter, followed by a discussion of obesity and related nutrition and medical issues. Finally, a discussion of analytical methods for body composition analysis and their application in PWS is presented (see Chapter 5 for a complete outline of Part II).

Original languageEnglish (US)
Title of host publicationManagement of Prader-Willi Syndrome
Subtitle of host publicationThird Edition
PublisherSpringer New York
Number of pages48
ISBN (Print)0387253971, 9780387253978
StatePublished - 2006
Externally publishedYes

ASJC Scopus subject areas

  • General Medicine


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