Abstract
GB virus C (GBV-C), a pan-lymphotropic flavivirus capable of persistent infection, is associated with prolonged survival and reduced T-cell activation in HIV-infected patients. GBV-C was associated with reduced CD56brt/CD16 natural killer cell and monocyte activation, and a trend toward reduced B-cell activation by measuring cell surface activation markers or HIV entry coreceptors. The GBV-C association was independent of HIV viral load. Thus, GBV-C may influence non-T-cell immune activation in individuals with HIV infection.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1829-1832 |
| Number of pages | 4 |
| Journal | AIDS |
| Volume | 27 |
| Issue number | 11 |
| DOIs | |
| State | Published - Jul 17 2013 |
| Externally published | Yes |
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology
- Infectious Diseases
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