Gender influence on plasma triacylglycerol response to meals with different monounsaturated and saturated fatty acid content

C. Koutsari, A. Zagana, I. Tzoras, L. S. Sidossis, A. L. Matalas

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Objective: Both gender and meal fatty acid composition modulate postprandial triacylglycerol (TAG) metabolism, but little information exists on their interaction. We compared postprandial TAG concentrations in men and women after test meals differing in the proportion of monounsaturated (MUFA) and saturated fatty acids (SFA). Subjects: Nine men (body mass index, BMI: 24.5± 2.3kg/m2) (mean±s.d.) and 10 premenopausal women (BMI: 21.2±1.7kg/m2), young and healthy, habituated to a relatively high MUFA diet. Design: Plasma responses were studied after subjects consumed two meals, each providing 60g of fat and 4.7 MJ, on different occasions: one meal was rich in MUFA (MUFA meal: 40g MUFA; 12g SFA) and the other meal was rich in SFA (SFA meal: 20g MUFA; 32g SFA). The total body and abdominal fat mass were assessed by dual energy X-ray absorptiometry. Results: Fasting plasma TAG concentration did not differ between meals or genders. No gender differences were observed in either total body or abdominal fat mass. The area under the plasma concentration vs time curve was on average 60% higher (P<0.001) in men than women. Repeated measures ANOVA showed a significant effect of meal × time interaction in men (P<0.001) but not in women (P=0.84). In men, maximal plasma TAG occurred at 4h and was significantly greater after the MUFA meal (2.10±0.20 mmol/l) (mean±s.e.m.) than after the SFA meal (1.66±0.19 mmol/l) (P=0.01). TAG concentration at 5h was also significantly greater after the MUFA meal. In women, the patterns of TAG responses were identical after the MUFA and SFA meals. Conclusions: This study provides evidence that gender influences postprandial TAG concentrations when meal fatty acid composition is altered.

Original languageEnglish (US)
Pages (from-to)495-502
Number of pages8
JournalEuropean Journal of Clinical Nutrition
Volume58
Issue number3
DOIs
StatePublished - Mar 2004
Externally publishedYes

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Monounsaturated Fatty Acids
meals (menu)
monounsaturated fatty acids
saturated fatty acids
Meals
Triglycerides
Fatty Acids
fatty acid composition
triacylglycerols
gender
Abdominal Fat
abdominal fat
body fat
Adipose Tissue
test meals
dual-energy X-ray absorptiometry
Photon Absorptiometry
gender differences
fasting
body mass index

Keywords

  • DXA
  • Men
  • Monounsaturated
  • Postprandial
  • Saturated
  • Triacylglycerol
  • Women

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Food Science

Cite this

Gender influence on plasma triacylglycerol response to meals with different monounsaturated and saturated fatty acid content. / Koutsari, C.; Zagana, A.; Tzoras, I.; Sidossis, L. S.; Matalas, A. L.

In: European Journal of Clinical Nutrition, Vol. 58, No. 3, 03.2004, p. 495-502.

Research output: Contribution to journalArticle

Koutsari, C. ; Zagana, A. ; Tzoras, I. ; Sidossis, L. S. ; Matalas, A. L. / Gender influence on plasma triacylglycerol response to meals with different monounsaturated and saturated fatty acid content. In: European Journal of Clinical Nutrition. 2004 ; Vol. 58, No. 3. pp. 495-502.
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abstract = "Objective: Both gender and meal fatty acid composition modulate postprandial triacylglycerol (TAG) metabolism, but little information exists on their interaction. We compared postprandial TAG concentrations in men and women after test meals differing in the proportion of monounsaturated (MUFA) and saturated fatty acids (SFA). Subjects: Nine men (body mass index, BMI: 24.5± 2.3kg/m2) (mean±s.d.) and 10 premenopausal women (BMI: 21.2±1.7kg/m2), young and healthy, habituated to a relatively high MUFA diet. Design: Plasma responses were studied after subjects consumed two meals, each providing 60g of fat and 4.7 MJ, on different occasions: one meal was rich in MUFA (MUFA meal: 40g MUFA; 12g SFA) and the other meal was rich in SFA (SFA meal: 20g MUFA; 32g SFA). The total body and abdominal fat mass were assessed by dual energy X-ray absorptiometry. Results: Fasting plasma TAG concentration did not differ between meals or genders. No gender differences were observed in either total body or abdominal fat mass. The area under the plasma concentration vs time curve was on average 60{\%} higher (P<0.001) in men than women. Repeated measures ANOVA showed a significant effect of meal × time interaction in men (P<0.001) but not in women (P=0.84). In men, maximal plasma TAG occurred at 4h and was significantly greater after the MUFA meal (2.10±0.20 mmol/l) (mean±s.e.m.) than after the SFA meal (1.66±0.19 mmol/l) (P=0.01). TAG concentration at 5h was also significantly greater after the MUFA meal. In women, the patterns of TAG responses were identical after the MUFA and SFA meals. Conclusions: This study provides evidence that gender influences postprandial TAG concentrations when meal fatty acid composition is altered.",
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