Genetic Associations With Intimate Partner Violence in a Sample of Hazardous Drinking Men in Batterer Intervention Programs

Gregory L. Stuart; John E. McGeary; Ryan C. Shorey; Valerie S. Knopik; Kayla Beaucage; Jeff R. Temple

doi:10.1177/1077801214528587

Genetic Associations With Intimate Partner Violence in a Sample of Hazardous Drinking Men in Batterer Intervention Programs

Gregory L. Stuart
, John E. McGeary
, Ryan C. Shorey
, Valerie S. Knopik
, Kayla Beaucage
, Jeff R. Temple

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Abstract

The etiology of intimate partner violence (IPV) is multifactorial. However, etiological theories of IPV have rarely included potential genetic factors. The purpose of the present study was to examine whether a cumulative genetic score (CGS) containing the monoamine oxidase A (MAOA) and the human serotonin transporter gene linked polymorphism (5-HTTLPR) was associated with IPV perpetration after accounting for the effects of alcohol problems, drug problems, age, and length of relationship. We obtained DNA from 97 men in batterer intervention programs in the state of Rhode Island. In the full sample, the CGS was significantly associated with physical and psychological aggression and injuries caused to one's partner, even after controlling for the effects of alcohol problems, drug problems, age, and length of relationship. Two of the men in the sample likely had Klinefelter's syndrome, and analyses were repeated excluding these two individuals, leading to similar results. The implications of the genetic findings for the etiology and treatment of IPV among men in batterer intervention programs are briefly discussed.

Original language	English (US)
Pages (from-to)	385-400
Number of pages	16
Journal	Violence Against Women
Volume	20
Issue number	4
DOIs	https://doi.org/10.1177/1077801214528587
State	Published - Apr 2014

Keywords

5-HTTPLR
MAOA
batterer intervention
genetics
intimate partner violence

ASJC Scopus subject areas

Gender Studies
Sociology and Political Science
Law

Access to Document

10.1177/1077801214528587

Cite this

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title = "Genetic Associations With Intimate Partner Violence in a Sample of Hazardous Drinking Men in Batterer Intervention Programs",

abstract = "The etiology of intimate partner violence (IPV) is multifactorial. However, etiological theories of IPV have rarely included potential genetic factors. The purpose of the present study was to examine whether a cumulative genetic score (CGS) containing the monoamine oxidase A (MAOA) and the human serotonin transporter gene linked polymorphism (5-HTTLPR) was associated with IPV perpetration after accounting for the effects of alcohol problems, drug problems, age, and length of relationship. We obtained DNA from 97 men in batterer intervention programs in the state of Rhode Island. In the full sample, the CGS was significantly associated with physical and psychological aggression and injuries caused to one's partner, even after controlling for the effects of alcohol problems, drug problems, age, and length of relationship. Two of the men in the sample likely had Klinefelter's syndrome, and analyses were repeated excluding these two individuals, leading to similar results. The implications of the genetic findings for the etiology and treatment of IPV among men in batterer intervention programs are briefly discussed.",

keywords = "5-HTTPLR, MAOA, batterer intervention, genetics, intimate partner violence",

author = "Stuart, \{Gregory L.\} and McGeary, \{John E.\} and Shorey, \{Ryan C.\} and Knopik, \{Valerie S.\} and Kayla Beaucage and Temple, \{Jeff R.\}",

note = "Funding Information: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This research was supported, in part, by Grants R01AA016315 and K24AA019707 from the National Institute on Alcohol Abuse and Alcoholism (Stuart, Principal Investigator), shared equipment grants (1S10RR023457-01A1) from the National Center for Research Resources and the Department of Veteran Affairs (John McGeary, Principal Investigator), and grant DA023134 from the National Institute on Drug Abuse (Knopik, Principal Investigator).",

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language = "English (US)",

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AU - Knopik, Valerie S.

AU - Beaucage, Kayla

AU - Temple, Jeff R.

N1 - Funding Information: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This research was supported, in part, by Grants R01AA016315 and K24AA019707 from the National Institute on Alcohol Abuse and Alcoholism (Stuart, Principal Investigator), shared equipment grants (1S10RR023457-01A1) from the National Center for Research Resources and the Department of Veteran Affairs (John McGeary, Principal Investigator), and grant DA023134 from the National Institute on Drug Abuse (Knopik, Principal Investigator).

PY - 2014/4

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N2 - The etiology of intimate partner violence (IPV) is multifactorial. However, etiological theories of IPV have rarely included potential genetic factors. The purpose of the present study was to examine whether a cumulative genetic score (CGS) containing the monoamine oxidase A (MAOA) and the human serotonin transporter gene linked polymorphism (5-HTTLPR) was associated with IPV perpetration after accounting for the effects of alcohol problems, drug problems, age, and length of relationship. We obtained DNA from 97 men in batterer intervention programs in the state of Rhode Island. In the full sample, the CGS was significantly associated with physical and psychological aggression and injuries caused to one's partner, even after controlling for the effects of alcohol problems, drug problems, age, and length of relationship. Two of the men in the sample likely had Klinefelter's syndrome, and analyses were repeated excluding these two individuals, leading to similar results. The implications of the genetic findings for the etiology and treatment of IPV among men in batterer intervention programs are briefly discussed.

AB - The etiology of intimate partner violence (IPV) is multifactorial. However, etiological theories of IPV have rarely included potential genetic factors. The purpose of the present study was to examine whether a cumulative genetic score (CGS) containing the monoamine oxidase A (MAOA) and the human serotonin transporter gene linked polymorphism (5-HTTLPR) was associated with IPV perpetration after accounting for the effects of alcohol problems, drug problems, age, and length of relationship. We obtained DNA from 97 men in batterer intervention programs in the state of Rhode Island. In the full sample, the CGS was significantly associated with physical and psychological aggression and injuries caused to one's partner, even after controlling for the effects of alcohol problems, drug problems, age, and length of relationship. Two of the men in the sample likely had Klinefelter's syndrome, and analyses were repeated excluding these two individuals, leading to similar results. The implications of the genetic findings for the etiology and treatment of IPV among men in batterer intervention programs are briefly discussed.

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Genetic Associations With Intimate Partner Violence in a Sample of Hazardous Drinking Men in Batterer Intervention Programs

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