Genetic factors controlling susceptibility to Leishmania major infection in the sand fly Phlebotomus papatasi (diptera: psychodidae)

W. K. Wu, R. B. Tesh

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Studies of the genetic factors controlling Leishmania major infection in Phlebotomus papatasi were carried out using 2 different sand fly lines: one highly susceptible and the other refractory to the parasite. L. major infection rates in both F1 and F2 generations from reciprocal crosses and in backcrosses between the parent lines showed that susceptibility and refractoriness of Ph. papatasi to infection with L. major are controlled by >1 gene. Neither susceptibility nor refractoriness is dominant over the other.

Original languageEnglish (US)
Pages (from-to)329-334
Number of pages6
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume42
Issue number4
StatePublished - 1990
Externally publishedYes

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Phlebotomus
Leishmania major
Psychodidae
Diptera
Infection
Parasites
Genes

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

Cite this

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