Genetic variation of Venezuelan equine encephalitis virus strains of the ID variety in Colombia

R. Rico-Hesse, J. T. Roehrig, D. W. Trent, R. W. Dickerman

Research output: Contribution to journalArticle

21 Scopus citations

Abstract

To determine the degree of genetic variation within one serologic group of Venezuelan equine encephalitis virus and the relatedness of viruses with different epidemiologic backgrounds isolated within the same country, virion RNA from 16 isolates belonging to subtype I were compared by RNase T1 oligonucleotide fingerprinting. RNA fingerprints of 12 enzootic isolates showed a large degree of heterogeneity, even though they were serologically indistinguishable. A reference enzootic strain from Colombia showed more genetic relatedness to three epizootic strains isolated in the same country, than to its own serogroup prototype strain isolated in Panama. Thus, genetic relatedness within Venezuelan equine encephalitis strains in Colombia seems to be a function of geography rather than epidemiology.

Original languageEnglish (US)
Pages (from-to)195-204
Number of pages10
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume38
Issue number1
DOIs
StatePublished - Jan 1 1988

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ASJC Scopus subject areas

  • Parasitology
  • Virology
  • Infectious Diseases

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