Genome structure of Ebola virus subtype Reston

Differences among Ebola subtypes

Tetsuro Ikegami, A. B. Calaor, M. E. Miranda, M. Niikura, M. Saijo, I. Kurane, Y. Yoshikawa, S. Morikawa

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

We determined the complete genome sequence of Ebola virus subtype Reston (EBO-R) in the Philippines in 1996. The deduced transcriptional signals were highly conserved among Ebola viruses except for the stop signal of L genes. The intergenic regions were composed of 4 to 7 nucleotides, and of 2 characteristic overlaps and a long intergenic region. The glycoprotein (GP) had several amino acid differences from EBO-R isolated in 1989 and 1992. The variety of GP sequences strongly suggests the independent introduction of EBO-R from unknown natural reservoirs in 1996.

Original languageEnglish (US)
Pages (from-to)2021-2027
Number of pages7
JournalArchives of Virology
Volume146
Issue number10
DOIs
StatePublished - 2001
Externally publishedYes

Fingerprint

Ebolavirus
Intergenic DNA
Glycoproteins
Genome
Philippines
Nucleotides
Amino Acids
Genes

ASJC Scopus subject areas

  • Genetics
  • Applied Microbiology and Biotechnology

Cite this

Ikegami, T., Calaor, A. B., Miranda, M. E., Niikura, M., Saijo, M., Kurane, I., ... Morikawa, S. (2001). Genome structure of Ebola virus subtype Reston: Differences among Ebola subtypes. Archives of Virology, 146(10), 2021-2027. https://doi.org/10.1007/s007050170049

Genome structure of Ebola virus subtype Reston : Differences among Ebola subtypes. / Ikegami, Tetsuro; Calaor, A. B.; Miranda, M. E.; Niikura, M.; Saijo, M.; Kurane, I.; Yoshikawa, Y.; Morikawa, S.

In: Archives of Virology, Vol. 146, No. 10, 2001, p. 2021-2027.

Research output: Contribution to journalArticle

Ikegami, T, Calaor, AB, Miranda, ME, Niikura, M, Saijo, M, Kurane, I, Yoshikawa, Y & Morikawa, S 2001, 'Genome structure of Ebola virus subtype Reston: Differences among Ebola subtypes', Archives of Virology, vol. 146, no. 10, pp. 2021-2027. https://doi.org/10.1007/s007050170049
Ikegami, Tetsuro ; Calaor, A. B. ; Miranda, M. E. ; Niikura, M. ; Saijo, M. ; Kurane, I. ; Yoshikawa, Y. ; Morikawa, S. / Genome structure of Ebola virus subtype Reston : Differences among Ebola subtypes. In: Archives of Virology. 2001 ; Vol. 146, No. 10. pp. 2021-2027.
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