Genomic and phylogenetic characterization of Leanyer virus, a novel orthobunyavirus isolated in northern Australia

Nazir Savji, Gustavo Palacios, Amelia Travassos da Rosa, Stephen Hutchison, Christopher Celone, Jeffrey Hui, Thomas Briese, Charles H. Calisher, Robert B. Tesh, W. Ian Lipkin

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Leanyer virus (LEAV), currently classified as a member of the genus Orthobunyavirus, in the family Bunyaviridae, was originally isolated from a pool of Anopheles meraukensis mosquitoes, collected at Leanyer, Northern Territory, Australia in 1974. When it failed to react in serological tests with antisera from other known viruses, full-length genomic sequencing was pursued to determine the relationship of LEAV to other orthobunyavirus species. Genetic and serological characterization confirmed its antigenic distance from other orthobunyaviruses, including to its closest genetic neighbours, the Simbu group viruses, suggesting that it may represent a new antigenic complex.

Original languageEnglish (US)
Pages (from-to)1676-1687
Number of pages12
JournalJournal of General Virology
Volume92
Issue number7
DOIs
StatePublished - Jul 2011

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Orthobunyavirus
Viruses
Simbu virus
Bunyaviridae
Northern Territory
Anopheles
Serologic Tests
Culicidae
Immune Sera

ASJC Scopus subject areas

  • Virology

Cite this

Savji, N., Palacios, G., da Rosa, A. T., Hutchison, S., Celone, C., Hui, J., ... Lipkin, W. I. (2011). Genomic and phylogenetic characterization of Leanyer virus, a novel orthobunyavirus isolated in northern Australia. Journal of General Virology, 92(7), 1676-1687. https://doi.org/10.1099/vir.0.028308-0

Genomic and phylogenetic characterization of Leanyer virus, a novel orthobunyavirus isolated in northern Australia. / Savji, Nazir; Palacios, Gustavo; da Rosa, Amelia Travassos; Hutchison, Stephen; Celone, Christopher; Hui, Jeffrey; Briese, Thomas; Calisher, Charles H.; Tesh, Robert B.; Lipkin, W. Ian.

In: Journal of General Virology, Vol. 92, No. 7, 07.2011, p. 1676-1687.

Research output: Contribution to journalArticle

Savji, N, Palacios, G, da Rosa, AT, Hutchison, S, Celone, C, Hui, J, Briese, T, Calisher, CH, Tesh, RB & Lipkin, WI 2011, 'Genomic and phylogenetic characterization of Leanyer virus, a novel orthobunyavirus isolated in northern Australia', Journal of General Virology, vol. 92, no. 7, pp. 1676-1687. https://doi.org/10.1099/vir.0.028308-0
Savji, Nazir ; Palacios, Gustavo ; da Rosa, Amelia Travassos ; Hutchison, Stephen ; Celone, Christopher ; Hui, Jeffrey ; Briese, Thomas ; Calisher, Charles H. ; Tesh, Robert B. ; Lipkin, W. Ian. / Genomic and phylogenetic characterization of Leanyer virus, a novel orthobunyavirus isolated in northern Australia. In: Journal of General Virology. 2011 ; Vol. 92, No. 7. pp. 1676-1687.
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