Abstract
Crimean-Congo hemorrhagic fever (CCHF) is a severe tick-borne disease caused by CCHF virus (CCHFV). Ticks in the genus Hyalomma are the main vectors and reservoirs of CCHFV. In Spain, CCHFV was first detected in Hyalomma ticks from Cáceres in 2010. Subsequently, two autochthonous CCHF cases were reported in August 2016. In this study, we describe the characterization of the CCHFV genome directly from Hyalomma lusitanicum collected in Cáceres in 2014. Phylogenetic analyses reveal a close relationship with clade III strains from West Africa, with an estimated divergence time of 50 years. The results of this work suggest that CCHFV has been circulating in Spain for some time, and most likely originated from West Africa.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 714-719 |
| Number of pages | 6 |
| Journal | Vector-Borne and Zoonotic Diseases |
| Volume | 17 |
| Issue number | 10 |
| DOIs | |
| State | Published - Oct 1 2017 |
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Keywords
- Crimean-Congo hemorrhagic fever (CCHF)
- emerging disease
- Hyalomma tick
- Spain
- tick-borne disease
ASJC Scopus subject areas
- Microbiology
- Infectious Diseases
- Virology
Cite this
Genomic Characterization of Crimean-Congo Hemorrhagic Fever Virus in Hyalomma Tick from Spain, 2014. / Cajimat, Maria N.B.; Rodriguez, Sergio; Schuster, Isolde U.E.; Swetnam, Daniele M.; Ksiazek, Thomas; Habela, Miguel A.; Negredo, Ana Isabel; Estrada-Peña, Agustín; Barrett, Alan; Bente, Dennis.
In: Vector-Borne and Zoonotic Diseases, Vol. 17, No. 10, 01.10.2017, p. 714-719.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Genomic Characterization of Crimean-Congo Hemorrhagic Fever Virus in Hyalomma Tick from Spain, 2014
AU - Cajimat, Maria N.B.
AU - Rodriguez, Sergio
AU - Schuster, Isolde U.E.
AU - Swetnam, Daniele M.
AU - Ksiazek, Thomas
AU - Habela, Miguel A.
AU - Negredo, Ana Isabel
AU - Estrada-Peña, Agustín
AU - Barrett, Alan
AU - Bente, Dennis
PY - 2017/10/1
Y1 - 2017/10/1
N2 - Crimean-Congo hemorrhagic fever (CCHF) is a severe tick-borne disease caused by CCHF virus (CCHFV). Ticks in the genus Hyalomma are the main vectors and reservoirs of CCHFV. In Spain, CCHFV was first detected in Hyalomma ticks from Cáceres in 2010. Subsequently, two autochthonous CCHF cases were reported in August 2016. In this study, we describe the characterization of the CCHFV genome directly from Hyalomma lusitanicum collected in Cáceres in 2014. Phylogenetic analyses reveal a close relationship with clade III strains from West Africa, with an estimated divergence time of 50 years. The results of this work suggest that CCHFV has been circulating in Spain for some time, and most likely originated from West Africa.
AB - Crimean-Congo hemorrhagic fever (CCHF) is a severe tick-borne disease caused by CCHF virus (CCHFV). Ticks in the genus Hyalomma are the main vectors and reservoirs of CCHFV. In Spain, CCHFV was first detected in Hyalomma ticks from Cáceres in 2010. Subsequently, two autochthonous CCHF cases were reported in August 2016. In this study, we describe the characterization of the CCHFV genome directly from Hyalomma lusitanicum collected in Cáceres in 2014. Phylogenetic analyses reveal a close relationship with clade III strains from West Africa, with an estimated divergence time of 50 years. The results of this work suggest that CCHFV has been circulating in Spain for some time, and most likely originated from West Africa.
KW - Crimean-Congo hemorrhagic fever (CCHF)
KW - emerging disease
KW - Hyalomma tick
KW - Spain
KW - tick-borne disease
UR - http://www.scopus.com/inward/record.url?scp=85030471694&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85030471694&partnerID=8YFLogxK
U2 - 10.1089/vbz.2017.2190
DO - 10.1089/vbz.2017.2190
M3 - Article
C2 - 28836897
AN - SCOPUS:85030471694
VL - 17
SP - 714
EP - 719
JO - Vector-Borne and Zoonotic Diseases
JF - Vector-Borne and Zoonotic Diseases
SN - 1530-3667
IS - 10
ER -