Genomic Characterization of Crimean-Congo Hemorrhagic Fever Virus in Hyalomma Tick from Spain, 2014

Maria N.B. Cajimat; Sergio Rodriguez; Isolde U.E. Schuster; Daniele M. Swetnam; Thomas Ksiazek; Miguel A. Habela; Ana Isabel Negredo; Agustín Estrada-Peña; Alan Barrett; Dennis Bente

doi:10.1089/vbz.2017.2190

Genomic Characterization of Crimean-Congo Hemorrhagic Fever Virus in Hyalomma Tick from Spain, 2014

Maria N.B. Cajimat, Sergio Rodriguez, Isolde U.E. Schuster, Daniele M. Swetnam, Thomas Ksiazek, Miguel A. Habela, Ana Isabel Negredo, Agustín Estrada-Peña, Alan Barrett, Dennis Bente

Research output: Contribution to journal › Article

6 Scopus citations

Abstract

Crimean-Congo hemorrhagic fever (CCHF) is a severe tick-borne disease caused by CCHF virus (CCHFV). Ticks in the genus Hyalomma are the main vectors and reservoirs of CCHFV. In Spain, CCHFV was first detected in Hyalomma ticks from Cáceres in 2010. Subsequently, two autochthonous CCHF cases were reported in August 2016. In this study, we describe the characterization of the CCHFV genome directly from Hyalomma lusitanicum collected in Cáceres in 2014. Phylogenetic analyses reveal a close relationship with clade III strains from West Africa, with an estimated divergence time of 50 years. The results of this work suggest that CCHFV has been circulating in Spain for some time, and most likely originated from West Africa.

Original language	English (US)
Pages (from-to)	714-719
Number of pages	6
Journal	Vector-Borne and Zoonotic Diseases
Volume	17
Issue number	10
DOIs	https://doi.org/10.1089/vbz.2017.2190
State	Published - Oct 1 2017

Fingerprint

Keywords

Crimean-Congo hemorrhagic fever (CCHF)
emerging disease
Hyalomma tick
Spain
tick-borne disease

ASJC Scopus subject areas

Microbiology
Infectious Diseases
Virology

Cite this

Cajimat, M. N. B., Rodriguez, S., Schuster, I. U. E., Swetnam, D. M., Ksiazek, T., Habela, M. A., Negredo, A. I., Estrada-Peña, A., Barrett, A., & Bente, D. (2017). Genomic Characterization of Crimean-Congo Hemorrhagic Fever Virus in Hyalomma Tick from Spain, 2014. Vector-Borne and Zoonotic Diseases, 17(10), 714-719. https://doi.org/10.1089/vbz.2017.2190

Genomic Characterization of Crimean-Congo Hemorrhagic Fever Virus in Hyalomma Tick from Spain, 2014. / Cajimat, Maria N.B.; Rodriguez, Sergio; Schuster, Isolde U.E.; Swetnam, Daniele M.; Ksiazek, Thomas; Habela, Miguel A.; Negredo, Ana Isabel; Estrada-Peña, Agustín; Barrett, Alan ; Bente, Dennis.

In: Vector-Borne and Zoonotic Diseases, Vol. 17, No. 10, 01.10.2017, p. 714-719.

Research output: Contribution to journal › Article

Cajimat, Maria N.B. ; Rodriguez, Sergio ; Schuster, Isolde U.E. ; Swetnam, Daniele M. ; Ksiazek, Thomas ; Habela, Miguel A. ; Negredo, Ana Isabel ; Estrada-Peña, Agustín ; Barrett, Alan ; Bente, Dennis. / Genomic Characterization of Crimean-Congo Hemorrhagic Fever Virus in Hyalomma Tick from Spain, 2014. In: Vector-Borne and Zoonotic Diseases. 2017 ; Vol. 17, No. 10. pp. 714-719.

@article{f0586ece299149ed9231e721b134c6ba,

title = "Genomic Characterization of Crimean-Congo Hemorrhagic Fever Virus in Hyalomma Tick from Spain, 2014",

abstract = "Crimean-Congo hemorrhagic fever (CCHF) is a severe tick-borne disease caused by CCHF virus (CCHFV). Ticks in the genus Hyalomma are the main vectors and reservoirs of CCHFV. In Spain, CCHFV was first detected in Hyalomma ticks from C{\'a}ceres in 2010. Subsequently, two autochthonous CCHF cases were reported in August 2016. In this study, we describe the characterization of the CCHFV genome directly from Hyalomma lusitanicum collected in C{\'a}ceres in 2014. Phylogenetic analyses reveal a close relationship with clade III strains from West Africa, with an estimated divergence time of 50 years. The results of this work suggest that CCHFV has been circulating in Spain for some time, and most likely originated from West Africa.",

keywords = "Crimean-Congo hemorrhagic fever (CCHF), emerging disease, Hyalomma tick, Spain, tick-borne disease",

author = "Cajimat, {Maria N.B.} and Sergio Rodriguez and Schuster, {Isolde U.E.} and Swetnam, {Daniele M.} and Thomas Ksiazek and Habela, {Miguel A.} and Negredo, {Ana Isabel} and Agust{\'i}n Estrada-Pe{\~n}a and Alan Barrett and Dennis Bente",

year = "2017",

month = oct

day = "1",

doi = "10.1089/vbz.2017.2190",

language = "English (US)",

volume = "17",

pages = "714--719",

journal = "Vector-Borne and Zoonotic Diseases",

issn = "1530-3667",

publisher = "Mary Ann Liebert Inc.",

number = "10",

}

TY - JOUR

T1 - Genomic Characterization of Crimean-Congo Hemorrhagic Fever Virus in Hyalomma Tick from Spain, 2014

AU - Cajimat, Maria N.B.

AU - Rodriguez, Sergio

AU - Schuster, Isolde U.E.

AU - Swetnam, Daniele M.

AU - Ksiazek, Thomas

AU - Habela, Miguel A.

AU - Negredo, Ana Isabel

AU - Estrada-Peña, Agustín

AU - Barrett, Alan

AU - Bente, Dennis

PY - 2017/10/1

Y1 - 2017/10/1

N2 - Crimean-Congo hemorrhagic fever (CCHF) is a severe tick-borne disease caused by CCHF virus (CCHFV). Ticks in the genus Hyalomma are the main vectors and reservoirs of CCHFV. In Spain, CCHFV was first detected in Hyalomma ticks from Cáceres in 2010. Subsequently, two autochthonous CCHF cases were reported in August 2016. In this study, we describe the characterization of the CCHFV genome directly from Hyalomma lusitanicum collected in Cáceres in 2014. Phylogenetic analyses reveal a close relationship with clade III strains from West Africa, with an estimated divergence time of 50 years. The results of this work suggest that CCHFV has been circulating in Spain for some time, and most likely originated from West Africa.

AB - Crimean-Congo hemorrhagic fever (CCHF) is a severe tick-borne disease caused by CCHF virus (CCHFV). Ticks in the genus Hyalomma are the main vectors and reservoirs of CCHFV. In Spain, CCHFV was first detected in Hyalomma ticks from Cáceres in 2010. Subsequently, two autochthonous CCHF cases were reported in August 2016. In this study, we describe the characterization of the CCHFV genome directly from Hyalomma lusitanicum collected in Cáceres in 2014. Phylogenetic analyses reveal a close relationship with clade III strains from West Africa, with an estimated divergence time of 50 years. The results of this work suggest that CCHFV has been circulating in Spain for some time, and most likely originated from West Africa.

KW - Crimean-Congo hemorrhagic fever (CCHF)

KW - emerging disease

KW - Hyalomma tick

KW - Spain

KW - tick-borne disease

UR - http://www.scopus.com/inward/record.url?scp=85030471694&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85030471694&partnerID=8YFLogxK

U2 - 10.1089/vbz.2017.2190

DO - 10.1089/vbz.2017.2190

M3 - Article

C2 - 28836897

AN - SCOPUS:85030471694

VL - 17

SP - 714

EP - 719

JO - Vector-Borne and Zoonotic Diseases

JF - Vector-Borne and Zoonotic Diseases

SN - 1530-3667

IS - 10

ER -

Access to Document

10.1089/vbz.2017.2190