Glucose-6-phosphatase as a marker for tumors of liver and kidney origin

Kimberlee Michals, Kevin Pringle, Emily J M Pang, Reuben Matalon

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Glucose-6-phosphatase is primarily a liver and kidney enzyme. This enzyme was studied in various tumors, however, glucose-6-phosphatase activity was found only in tumors of liver, kidney, or adrenal origin. Glucose-6-phosphatase activity was useful in identifying the tissue origin of extrarenal Wilms'. Metastatic tumors within the liver or kidney that originated from other tissues did not have glucose-6-phosphatase activity. Therefore, it is suggested that glucose-6-phosphatase can be used as a specific enzyme marker for tumors of liver and kidney origin.

Original languageEnglish (US)
Pages (from-to)127-130
Number of pages4
JournalBiochemical Medicine
Volume30
Issue number1
DOIs
StatePublished - 1983
Externally publishedYes

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Glucose-6-Phosphatase
Tumor Biomarkers
Liver
Kidney
Tumors
Enzymes
Tissue
Neoplasms

ASJC Scopus subject areas

  • Biochemistry

Cite this

Glucose-6-phosphatase as a marker for tumors of liver and kidney origin. / Michals, Kimberlee; Pringle, Kevin; Pang, Emily J M; Matalon, Reuben.

In: Biochemical Medicine, Vol. 30, No. 1, 1983, p. 127-130.

Research output: Contribution to journalArticle

Michals, Kimberlee ; Pringle, Kevin ; Pang, Emily J M ; Matalon, Reuben. / Glucose-6-phosphatase as a marker for tumors of liver and kidney origin. In: Biochemical Medicine. 1983 ; Vol. 30, No. 1. pp. 127-130.
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