Glutamate dehydrogenase: Structure of a hyperinsulinism mutant, corrections to the atomic model, and insights into a regulatory site

Keyphrases

• Hyperinsulinism 100%
• Glutamate Dehydrogenase 100%
• Hyperinsulinism/hyperammonemia Syndrome 100%
• Atomic Model 100%
• Regulatory Site 100%
• Atomic Insights 100%
• Insulin 40%
• Sequencing Error 40%
• Drug Development 20%
• Genetic Disease 20%
• Binding Site 20%
• Asparagine 20%
• Computational Analysis 20%
• Allosteric Regulation 20%
• Lysine 20%
• Atomic Structure 20%
• Hyperammonemia 20%
• Binding Energy 20%
• Binding Pocket 20%
• GTP Binding 20%
• Free Energy Perturbation 20%
• Amino Acid Catabolism 20%
• Large Deviations 20%
• Energy Penalty 20%

Biochemistry, Genetics and Molecular Biology

• Glutamate Dehydrogenase 100%
• Regulatory Site 100%
• Crystal Structure 50%
• Guanosine Triphosphate 50%
• Metabolite 25%
• Enzyme 25%
• Amino Acids 25%
• Genetic Disorder 25%
• Binding Site 25%
• Asparagine 25%
• Allosteric Regulation 25%
• Lysine 25%
• Drug Development 25%

Pharmacology, Toxicology and Pharmaceutical Science

• Glutamate Dehydrogenase 100%
• Hyperinsulinism 100%
• Hyperammonemia 85%
• Syndrome 71%
• Guanosine Triphosphate 28%
• Drug Development 14%
• Amino Acid 14%
• Genetic Disorder 14%
• Binding Site 14%
• Lysine 14%
• Asparagine 14%
• Diseases 14%