Glutamate receptors and their role in acute and inflammatory pain

Susan M. Carlton

    Research output: Chapter in Book/Report/Conference proceedingChapter

    2 Scopus citations

    Abstract

    7. Summary: Data from both animals and humans indicate that peripheral glutamate receptors are involved in nociceptive transmission in the normal and inflamed state. Studies in animal models indicate that peripheral glutamate receptors may provide novel targets for treatment of inflammatory pain. The variety of peripheral iGlu and mGlu receptors provides many targets for drug development. Manipulating the peripheral glutamatergic system could lead to advances in treating maladaptive pain while avoiding CNS side effects.

    Original languageEnglish (US)
    Title of host publicationGlutamate Receptors in Peripheral Tissue
    Subtitle of host publicationExcitatory Transmission Outside the CNS
    PublisherSpringer US
    Pages87-96
    Number of pages10
    ISBN (Electronic)9780306486449
    ISBN (Print)0306479737, 9780306479731
    DOIs
    StatePublished - Jan 1 2005

    ASJC Scopus subject areas

    • Medicine(all)
    • Neuroscience(all)

    Fingerprint Dive into the research topics of 'Glutamate receptors and their role in acute and inflammatory pain'. Together they form a unique fingerprint.

  • Cite this

    Carlton, S. M. (2005). Glutamate receptors and their role in acute and inflammatory pain. In Glutamate Receptors in Peripheral Tissue: Excitatory Transmission Outside the CNS (pp. 87-96). Springer US. https://doi.org/10.1007/0-306-48644-X_5