Glutamate receptors and their role in acute and inflammatory pain

Susan M. Carlton

doi:10.1007/0-306-48644-X_5

Glutamate receptors and their role in acute and inflammatory pain

Susan M. Carlton

Research output: Chapter in Book/Report/Conference proceeding › Chapter

3 Scopus citations

Abstract

7. Summary: Data from both animals and humans indicate that peripheral glutamate receptors are involved in nociceptive transmission in the normal and inflamed state. Studies in animal models indicate that peripheral glutamate receptors may provide novel targets for treatment of inflammatory pain. The variety of peripheral iGlu and mGlu receptors provides many targets for drug development. Manipulating the peripheral glutamatergic system could lead to advances in treating maladaptive pain while avoiding CNS side effects.

Original language	English (US)
Title of host publication	Glutamate Receptors in Peripheral Tissue
Subtitle of host publication	Excitatory Transmission Outside the CNS
Publisher	Springer US
Pages	87-96
Number of pages	10
ISBN (Electronic)	9780306486449
ISBN (Print)	0306479737, 9780306479731
DOIs	https://doi.org/10.1007/0-306-48644-X_5
State	Published - 2005

ASJC Scopus subject areas

General Medicine
General Neuroscience

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10.1007/0-306-48644-X_5

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AB - 7. Summary: Data from both animals and humans indicate that peripheral glutamate receptors are involved in nociceptive transmission in the normal and inflamed state. Studies in animal models indicate that peripheral glutamate receptors may provide novel targets for treatment of inflammatory pain. The variety of peripheral iGlu and mGlu receptors provides many targets for drug development. Manipulating the peripheral glutamatergic system could lead to advances in treating maladaptive pain while avoiding CNS side effects.

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M3 - Chapter

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BT - Glutamate Receptors in Peripheral Tissue

PB - Springer US

ER -

Glutamate receptors and their role in acute and inflammatory pain

Abstract

ASJC Scopus subject areas

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