Glutamine Kinetics in Burn Patients: Comparison With Hormonally Induced Stress in Volunteers

Dennis C. Gore, Farook Jahoor

Research output: Contribution to journalArticle

63 Scopus citations

Abstract

These findings suggest that in the acute stress response, skeletal muscle preferentially releases glutamine from its free intracellular pool. As this reserve becomes depleted, net glutamine efflux is maintained by decreasing its rate of muscle glutamine utilization. These results suggest a failure of muscle to augment de novo glutamine synthesis and support the conclusion that glutamine is a conditionally essential amino acid during critical illness. (Arch Surg. 1994;129:1318-1323).

Original languageEnglish (US)
Pages (from-to)1318-1323
Number of pages6
JournalArchives of Surgery
Volume129
Issue number12
DOIs
StatePublished - Dec 1994
Externally publishedYes

ASJC Scopus subject areas

  • Surgery

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