These findings suggest that in the acute stress response, skeletal muscle preferentially releases glutamine from its free intracellular pool. As this reserve becomes depleted, net glutamine efflux is maintained by decreasing its rate of muscle glutamine utilization. These results suggest a failure of muscle to augment de novo glutamine synthesis and support the conclusion that glutamine is a conditionally essential amino acid during critical illness. (Arch Surg. 1994;129:1318-1323).
|Original language||English (US)|
|Number of pages||6|
|Journal||Archives of Surgery|
|State||Published - Dec 1994|
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