Glutamine-supplemented nutrition supports the intestinal mucosa

D. W. Wilmore, S. T. O'Dwyer, D. O. Jacobs, X. Wang, R. J. Smith

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Glutamine is an essential nutrient for the intestinal mucosa and other rapidly dividing cells. Glutamine is not present in standard parenteral nutrient solutions. When glutamine is added to both parenteral and enteral formulas, there is enhanced mucosal cellularity and repair. These changes are related to diminished mortality and morbidity in selected animal models. Glutamine-containing solutions are now being administered safely to patients. Studies are required to determine the effects of such therapy in individuals following extensive radiation or chemotherapy, major burns or infections and those with inflammatory bowel disease. It appears that selected nutritional support utilizing glutamine-containing nutrition can now be provided to maintain and support growth of the gastrointestinal mucosa.

Original languageEnglish (US)
Title of host publicationNutritional support in organ failure: proceedings of the International Symposium. ICS836
EditorsT. Tanaka, A. Okada, T. Tanaka, A. Okada
PublisherElsevier Science Publishers B.V.
Pages217-225
Number of pages9
ISBN (Print)0444811613
StatePublished - 1990
Externally publishedYes
EventThe International Symposium -
Duration: Nov 21 1988Nov 23 1988

Other

OtherThe International Symposium
Period11/21/8811/23/88

Fingerprint

Intestinal Mucosa
Glutamine
Nutritional Support
Burns
Inflammatory Bowel Diseases
Small Intestine
Mucous Membrane
Animal Models
Radiation
Morbidity
Drug Therapy
Food
Mortality
Growth
Infection
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Wilmore, D. W., O'Dwyer, S. T., Jacobs, D. O., Wang, X., & Smith, R. J. (1990). Glutamine-supplemented nutrition supports the intestinal mucosa. In T. Tanaka, A. Okada, T. Tanaka, & A. Okada (Eds.), Nutritional support in organ failure: proceedings of the International Symposium. ICS836 (pp. 217-225). Elsevier Science Publishers B.V..

Glutamine-supplemented nutrition supports the intestinal mucosa. / Wilmore, D. W.; O'Dwyer, S. T.; Jacobs, D. O.; Wang, X.; Smith, R. J.

Nutritional support in organ failure: proceedings of the International Symposium. ICS836. ed. / T. Tanaka; A. Okada; T. Tanaka; A. Okada. Elsevier Science Publishers B.V., 1990. p. 217-225.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Wilmore, DW, O'Dwyer, ST, Jacobs, DO, Wang, X & Smith, RJ 1990, Glutamine-supplemented nutrition supports the intestinal mucosa. in T Tanaka, A Okada, T Tanaka & A Okada (eds), Nutritional support in organ failure: proceedings of the International Symposium. ICS836. Elsevier Science Publishers B.V., pp. 217-225, The International Symposium, 11/21/88.
Wilmore DW, O'Dwyer ST, Jacobs DO, Wang X, Smith RJ. Glutamine-supplemented nutrition supports the intestinal mucosa. In Tanaka T, Okada A, Tanaka T, Okada A, editors, Nutritional support in organ failure: proceedings of the International Symposium. ICS836. Elsevier Science Publishers B.V. 1990. p. 217-225
Wilmore, D. W. ; O'Dwyer, S. T. ; Jacobs, D. O. ; Wang, X. ; Smith, R. J. / Glutamine-supplemented nutrition supports the intestinal mucosa. Nutritional support in organ failure: proceedings of the International Symposium. ICS836. editor / T. Tanaka ; A. Okada ; T. Tanaka ; A. Okada. Elsevier Science Publishers B.V., 1990. pp. 217-225
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