Glutathione and related enzymes in fascioliasis before and after treatment with bithionol

Sherif Abdel-Rahman, A. M. El-Sharkawy, L. M. Abou-Bacha, A. Salem

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The present work is an update evaluation of the glutathione status in patients with established fascioliasis before and after treatment with bithionol. Blood glutathione (GSH), erythrocyte glutathione S-transferase (GST) and serum γ-glutamyl transferase (GGT) activities were studied. After treatment, the variation observed in these parameters were restored to the corresponding normal control values confirming the toxic features resulting from fascioliasis and suggesting no adverse effect of bithionol on the parameters studied. We recommend the use of serum GGT, blood GSH and erythrocyte GST for the early detection of therapeutic response in fascioliasis.

Original languageEnglish (US)
Pages (from-to)337-340
Number of pages4
JournalJournal of Tropical Medicine and Hygiene
Volume93
Issue number5
StatePublished - 1990
Externally publishedYes

Fingerprint

Bithionol
Fascioliasis
Glutathione
serum
Enzymes
enzyme
Transferases
Glutathione Transferase
Erythrocytes
blood
Serum
Blood
Poisons
Reference Values
Therapeutics
parameter

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

Cite this

Glutathione and related enzymes in fascioliasis before and after treatment with bithionol. / Abdel-Rahman, Sherif; El-Sharkawy, A. M.; Abou-Bacha, L. M.; Salem, A.

In: Journal of Tropical Medicine and Hygiene, Vol. 93, No. 5, 1990, p. 337-340.

Research output: Contribution to journalArticle

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