Glycemic control in the burn intensive care unit: Focus on the role of anemia in glucose measurement

Elizabeth A. Mann, Alejandra G. Mora, Heather F. Pidcoke, Steven Wolf, Charles E. Wade

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Glycemic control with intensive insulin therapy (IIT) has received widespread adoption secondary to findings of improved clinical outcomes and survival in the burn population. Severe burn as a model for trauma is characterized by a hypermetabolic state, hyperglycemia, and insulin resistance. In this article, we review the findings of a burn center research facility in terms of understanding glucose management. The conferred benefits from IIT, our findings of poor outcomes associated with glycemic variability, advantages from preserved diurnal variation of glucose and insulin, and impacts of glucometer error and hematocrit correction factor are discussed. We conclude with direction for further study and the need for a reliable continuous glucose monitoring system. Such efforts will further the endeavor for achieving adequate glycemic control in order to assess the efficacy of target ranges and use of IIT.

Original languageEnglish (US)
Pages (from-to)1319-1329
Number of pages11
JournalJournal of diabetes science and technology
Volume3
Issue number6
DOIs
StatePublished - Jan 1 2009
Externally publishedYes

Fingerprint

Intensive care units
Insulin
Intensive Care Units
Glucose
Anemia
Burn Units
Hematocrit
Hyperglycemia
Insulin Resistance
Therapeutics
Wounds and Injuries
Research
Monitoring
Population

Keywords

  • Artificial pancreas
  • Burn
  • Computer decision support
  • Continuous glucose monitor
  • Diurnal variation
  • Glucometer
  • Glucose variability
  • Hematocrit effect
  • Hypoglycemia
  • Intensive insulin therapy

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Bioengineering
  • Biomedical Engineering

Cite this

Glycemic control in the burn intensive care unit : Focus on the role of anemia in glucose measurement. / Mann, Elizabeth A.; Mora, Alejandra G.; Pidcoke, Heather F.; Wolf, Steven; Wade, Charles E.

In: Journal of diabetes science and technology, Vol. 3, No. 6, 01.01.2009, p. 1319-1329.

Research output: Contribution to journalArticle

Mann, Elizabeth A. ; Mora, Alejandra G. ; Pidcoke, Heather F. ; Wolf, Steven ; Wade, Charles E. / Glycemic control in the burn intensive care unit : Focus on the role of anemia in glucose measurement. In: Journal of diabetes science and technology. 2009 ; Vol. 3, No. 6. pp. 1319-1329.
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