Glycolipid and mucopolysaccharide abnormality in fibroblasts of Fabry's disease

Reuben Matalon, Albert Dorfman, Glyn Dawson, Charles C. Sweeley

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Cultures of skin fiibroblasts from a patient with Fabry's disease showed an accumulation of the glycolipid, galactosyl-galactosyl-glucosyl ceramide. Such cells also showed metachromasia on staining with toluidine blue and a markedly elevated acid mucopolysaccharide content.

Original languageEnglish (US)
Pages (from-to)1522-1523
Number of pages2
JournalScience
Volume164
Issue number3887
StatePublished - 1969
Externally publishedYes

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Galactosylceramides
Glucosylceramides
Fabry Disease
Tolonium Chloride
Glycolipids
Glycosaminoglycans
Fibroblasts
Staining and Labeling
Skin
Acids

ASJC Scopus subject areas

  • General

Cite this

Matalon, R., Dorfman, A., Dawson, G., & Sweeley, C. C. (1969). Glycolipid and mucopolysaccharide abnormality in fibroblasts of Fabry's disease. Science, 164(3887), 1522-1523.

Glycolipid and mucopolysaccharide abnormality in fibroblasts of Fabry's disease. / Matalon, Reuben; Dorfman, Albert; Dawson, Glyn; Sweeley, Charles C.

In: Science, Vol. 164, No. 3887, 1969, p. 1522-1523.

Research output: Contribution to journalArticle

Matalon, R, Dorfman, A, Dawson, G & Sweeley, CC 1969, 'Glycolipid and mucopolysaccharide abnormality in fibroblasts of Fabry's disease', Science, vol. 164, no. 3887, pp. 1522-1523.
Matalon R, Dorfman A, Dawson G, Sweeley CC. Glycolipid and mucopolysaccharide abnormality in fibroblasts of Fabry's disease. Science. 1969;164(3887):1522-1523.
Matalon, Reuben ; Dorfman, Albert ; Dawson, Glyn ; Sweeley, Charles C. / Glycolipid and mucopolysaccharide abnormality in fibroblasts of Fabry's disease. In: Science. 1969 ; Vol. 164, No. 3887. pp. 1522-1523.
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