Graft-versus-host disease: gastrointestinal involvement with a rectovaginal fistula.

B. H. Kessler, W. J. Cochran, M. L. Wagner, H. K. Hawkins, W. J. Klish

Research output: Contribution to journalArticle

Abstract

Bone marrow transplantation is an accepted form of treatment for aplastic anemia and end-stage hematological malignancies. Despite a satisfactory outcome in selected patients, more than one-half develop acute graft-versus-host disease (GVHD), characterized typically by involvement of the skin, liver, and gastrointestinal tract. We describe an unusual case in which a 10-year-old girl developed gastrointestinal symptoms as the only manifestation of GVHD. The patient presented with a rectovaginal fistula and had clinical, radiological, and histological features of gastrointestinal GVHD without evidence of liver or skin involvement.

Original languageEnglish (US)
Pages (from-to)288-292
Number of pages5
JournalJournal of Pediatric Gastroenterology and Nutrition
Volume7
Issue number2
StatePublished - Mar 1988
Externally publishedYes

Fingerprint

Rectovaginal Fistula
fistula
Graft vs Host Disease
digestive system diseases
skin (animal)
bone marrow transplant
liver
anemia
signs and symptoms (animals and humans)
gastrointestinal system
Skin
Aplastic Anemia
Liver
Hematologic Neoplasms
Bone Marrow Transplantation
Gastrointestinal Tract
Therapeutics

ASJC Scopus subject areas

  • Food Science
  • Medicine (miscellaneous)
  • Gastroenterology
  • Histology
  • Pediatrics, Perinatology, and Child Health

Cite this

Kessler, B. H., Cochran, W. J., Wagner, M. L., Hawkins, H. K., & Klish, W. J. (1988). Graft-versus-host disease: gastrointestinal involvement with a rectovaginal fistula. Journal of Pediatric Gastroenterology and Nutrition, 7(2), 288-292.

Graft-versus-host disease : gastrointestinal involvement with a rectovaginal fistula. / Kessler, B. H.; Cochran, W. J.; Wagner, M. L.; Hawkins, H. K.; Klish, W. J.

In: Journal of Pediatric Gastroenterology and Nutrition, Vol. 7, No. 2, 03.1988, p. 288-292.

Research output: Contribution to journalArticle

Kessler, BH, Cochran, WJ, Wagner, ML, Hawkins, HK & Klish, WJ 1988, 'Graft-versus-host disease: gastrointestinal involvement with a rectovaginal fistula.', Journal of Pediatric Gastroenterology and Nutrition, vol. 7, no. 2, pp. 288-292.
Kessler, B. H. ; Cochran, W. J. ; Wagner, M. L. ; Hawkins, H. K. ; Klish, W. J. / Graft-versus-host disease : gastrointestinal involvement with a rectovaginal fistula. In: Journal of Pediatric Gastroenterology and Nutrition. 1988 ; Vol. 7, No. 2. pp. 288-292.
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