Graft-versus-host disease: gastrointestinal involvement with a rectovaginal fistula.

B. H. Kessler, W. J. Cochran, M. L. Wagner, H. K. Hawkins, W. J. Klish

Research output: Contribution to journalArticle

Abstract

Bone marrow transplantation is an accepted form of treatment for aplastic anemia and end-stage hematological malignancies. Despite a satisfactory outcome in selected patients, more than one-half develop acute graft-versus-host disease (GVHD), characterized typically by involvement of the skin, liver, and gastrointestinal tract. We describe an unusual case in which a 10-year-old girl developed gastrointestinal symptoms as the only manifestation of GVHD. The patient presented with a rectovaginal fistula and had clinical, radiological, and histological features of gastrointestinal GVHD without evidence of liver or skin involvement.

Original languageEnglish (US)
Pages (from-to)288-292
Number of pages5
JournalJournal of Pediatric Gastroenterology and Nutrition
Volume7
Issue number2
StatePublished - Mar 1988
Externally publishedYes

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ASJC Scopus subject areas

  • Food Science
  • Medicine (miscellaneous)
  • Gastroenterology
  • Histology
  • Pediatrics, Perinatology, and Child Health

Cite this

Kessler, B. H., Cochran, W. J., Wagner, M. L., Hawkins, H. K., & Klish, W. J. (1988). Graft-versus-host disease: gastrointestinal involvement with a rectovaginal fistula. Journal of Pediatric Gastroenterology and Nutrition, 7(2), 288-292.