Granular corneal dystrophy manifesting after radial keratotomy

Sepehr Feizi; Mohammad Pakravan; Ali Reza Baradaran-Rafiee; Shahin Yazdani

doi:10.1097/ICO.0b013e3181450fa8

Granular corneal dystrophy manifesting after radial keratotomy

Sepehr Feizi, Mohammad Pakravan, Ali Reza Baradaran-Rafiee, Shahin Yazdani

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

PURPOSE: To report a case of granular corneal dystrophy after radial keratotomy (RK). METHODS: A 32-year-old man presented with white radial lines in both corneas. He had a history of uncomplicated RK in both eyes 8 years ago. Preoperative refraction had been OD -3.5-0.75 × 180 and OS -3.0-0.5 × 175. The cornea was reported to be clear on postoperative examinations. RESULTS: Postoperative uncorrected visual acuity was OD 20/30 and OS 20/40. Best-corrected visual acuity was 20/25 in both eyes with OD -0.5-0.5 × 60 and OS -0.75-0.5 × 80. Slit-lamp examination revealed discrete well-demarcated whitish lesions with clear intervening stroma in the central anterior cornea consistent with granular dystrophy. Similar opacities were present within the RK incisions. CONCLUSIONS: Production and deposition of such abnormal material could be due to keratocyte activation after RK or proliferation and migration of epithelial cells with a tendency to express abnormal keratoepithelin.

Original language	English (US)
Pages (from-to)	1267-1269
Number of pages	3
Journal	Cornea
Volume	26
Issue number	10
DOIs	https://doi.org/10.1097/ICO.0b013e3181450fa8
State	Published - Dec 2007
Externally published	Yes

Keywords

Granular corneal dystrophy
Keratoepithelin
Radial keratotomy

ASJC Scopus subject areas

Ophthalmology

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10.1097/ICO.0b013e3181450fa8

Cite this

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title = "Granular corneal dystrophy manifesting after radial keratotomy",

abstract = "PURPOSE: To report a case of granular corneal dystrophy after radial keratotomy (RK). METHODS: A 32-year-old man presented with white radial lines in both corneas. He had a history of uncomplicated RK in both eyes 8 years ago. Preoperative refraction had been OD -3.5-0.75 × 180 and OS -3.0-0.5 × 175. The cornea was reported to be clear on postoperative examinations. RESULTS: Postoperative uncorrected visual acuity was OD 20/30 and OS 20/40. Best-corrected visual acuity was 20/25 in both eyes with OD -0.5-0.5 × 60 and OS -0.75-0.5 × 80. Slit-lamp examination revealed discrete well-demarcated whitish lesions with clear intervening stroma in the central anterior cornea consistent with granular dystrophy. Similar opacities were present within the RK incisions. CONCLUSIONS: Production and deposition of such abnormal material could be due to keratocyte activation after RK or proliferation and migration of epithelial cells with a tendency to express abnormal keratoepithelin.",

keywords = "Granular corneal dystrophy, Keratoepithelin, Radial keratotomy",

author = "Sepehr Feizi and Mohammad Pakravan and Baradaran-Rafiee, {Ali Reza} and Shahin Yazdani",

year = "2007",

month = dec,

doi = "10.1097/ICO.0b013e3181450fa8",

language = "English (US)",

volume = "26",

pages = "1267--1269",

journal = "Cornea",

issn = "0277-3740",

publisher = "Lippincott Williams and Wilkins",

number = "10",

}

TY - JOUR

T1 - Granular corneal dystrophy manifesting after radial keratotomy

AU - Feizi, Sepehr

AU - Pakravan, Mohammad

AU - Baradaran-Rafiee, Ali Reza

AU - Yazdani, Shahin

PY - 2007/12

Y1 - 2007/12

N2 - PURPOSE: To report a case of granular corneal dystrophy after radial keratotomy (RK). METHODS: A 32-year-old man presented with white radial lines in both corneas. He had a history of uncomplicated RK in both eyes 8 years ago. Preoperative refraction had been OD -3.5-0.75 × 180 and OS -3.0-0.5 × 175. The cornea was reported to be clear on postoperative examinations. RESULTS: Postoperative uncorrected visual acuity was OD 20/30 and OS 20/40. Best-corrected visual acuity was 20/25 in both eyes with OD -0.5-0.5 × 60 and OS -0.75-0.5 × 80. Slit-lamp examination revealed discrete well-demarcated whitish lesions with clear intervening stroma in the central anterior cornea consistent with granular dystrophy. Similar opacities were present within the RK incisions. CONCLUSIONS: Production and deposition of such abnormal material could be due to keratocyte activation after RK or proliferation and migration of epithelial cells with a tendency to express abnormal keratoepithelin.

AB - PURPOSE: To report a case of granular corneal dystrophy after radial keratotomy (RK). METHODS: A 32-year-old man presented with white radial lines in both corneas. He had a history of uncomplicated RK in both eyes 8 years ago. Preoperative refraction had been OD -3.5-0.75 × 180 and OS -3.0-0.5 × 175. The cornea was reported to be clear on postoperative examinations. RESULTS: Postoperative uncorrected visual acuity was OD 20/30 and OS 20/40. Best-corrected visual acuity was 20/25 in both eyes with OD -0.5-0.5 × 60 and OS -0.75-0.5 × 80. Slit-lamp examination revealed discrete well-demarcated whitish lesions with clear intervening stroma in the central anterior cornea consistent with granular dystrophy. Similar opacities were present within the RK incisions. CONCLUSIONS: Production and deposition of such abnormal material could be due to keratocyte activation after RK or proliferation and migration of epithelial cells with a tendency to express abnormal keratoepithelin.

KW - Granular corneal dystrophy

KW - Keratoepithelin

KW - Radial keratotomy

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Granular corneal dystrophy manifesting after radial keratotomy

Abstract

Keywords

ASJC Scopus subject areas

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