Granular corneal dystrophy manifesting after radial keratotomy

Sepehr Feizi, Mohammad Pakravan, Ali Reza Baradaran-Rafiee, Shahin Yazdani

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


PURPOSE: To report a case of granular corneal dystrophy after radial keratotomy (RK). METHODS: A 32-year-old man presented with white radial lines in both corneas. He had a history of uncomplicated RK in both eyes 8 years ago. Preoperative refraction had been OD -3.5-0.75 × 180 and OS -3.0-0.5 × 175. The cornea was reported to be clear on postoperative examinations. RESULTS: Postoperative uncorrected visual acuity was OD 20/30 and OS 20/40. Best-corrected visual acuity was 20/25 in both eyes with OD -0.5-0.5 × 60 and OS -0.75-0.5 × 80. Slit-lamp examination revealed discrete well-demarcated whitish lesions with clear intervening stroma in the central anterior cornea consistent with granular dystrophy. Similar opacities were present within the RK incisions. CONCLUSIONS: Production and deposition of such abnormal material could be due to keratocyte activation after RK or proliferation and migration of epithelial cells with a tendency to express abnormal keratoepithelin.

Original languageEnglish (US)
Pages (from-to)1267-1269
Number of pages3
Issue number10
StatePublished - Dec 2007
Externally publishedYes


  • Granular corneal dystrophy
  • Keratoepithelin
  • Radial keratotomy

ASJC Scopus subject areas

  • Ophthalmology


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