Growth hormone deficiency in adults: Characteristics and response to growth hormone replacement

S. A. Lieberman, A. R. Hoffman

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

Despite adequate adrenal, gonadal, and thyroid hormone replacement, many adults with hypopituitarism have a recognizable syndrome of weakness and diminished sense of well-being, accompanied by alterations in metabolism and body composition, as well as increased mortality. Short-term treatment with human growth hormone improves many of these abnormalities, but a clear improvement in functional status has yet to be demonstrated. Until such an effect is shown, the use of growth hormone replacement in adults with hypopituitarism remains investigational.

Original languageEnglish (US)
Pages (from-to)S58-S60
JournalJournal of Pediatrics
Volume128
Issue number5 II
DOIs
StatePublished - 1996

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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