Despite adequate adrenal, gonadal, and thyroid hormone replacement, many adults with hypopituitarism have a recognizable syndrome of weakness and diminished sense of well-being, accompanied by alterations in metabolism and body composition, as well as increased mortality. Short-term treatment with human growth hormone improves many of these abnormalities, but a clear improvement in functional status has yet to be demonstrated. Until such an effect is shown, the use of growth hormone replacement in adults with hypopituitarism remains investigational.
|Original language||English (US)|
|Journal||Journal of Pediatrics|
|Issue number||5 II|
|State||Published - May 20 1996|
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health