Growth hormone treatment for burned children

D. N. Herndon, E. J. Pierre, K. N. Stokes, R. E. Barrow

Research output: Contribution to journalArticle

16 Scopus citations

Abstract

Several growth hormones show promise in the treatment of burn injuries, particularly for paediatric patients. Animal studies and clinical trials indicate that growth hormones help modulate the devastating effects of the hypermetabolic response to burn injury and improve wound healing. Recombinant human growth hormone (rhGH) has been shown to reduce loss of body weight, stimulate protein synthesis, increase epithelial cell proliferation, and accelerate wound healing. Accelerated wound closure reduces the risk of infection, shortens hospital stay, and lowers overall medical costs. Current investigations are in progress to determine the effects of rhGH on anabolic growth arrests experienced by paediatric burn survivors.

Original languageEnglish (US)
Pages (from-to)29-31
Number of pages3
JournalHormone Research in Paediatrics
Volume45
DOIs
StatePublished - Jan 1996

Keywords

  • Burns
  • Growth hormone
  • Hypermetabolism
  • Insulin
  • Insulin-like growth factor
  • Paediatric

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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    Herndon, D. N., Pierre, E. J., Stokes, K. N., & Barrow, R. E. (1996). Growth hormone treatment for burned children. Hormone Research in Paediatrics, 45, 29-31. https://doi.org/10.1159/000184825