Growth hormone treatment for burned children

David Herndon, E. J. Pierre, K. N. Stokes, R. E. Barrow

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Several growth hormones show promise in the treatment of burn injuries, particularly for paediatric patients. Animal studies and clinical trials indicate that growth hormones help modulate the devastating effects of the hypermetabolic response to burn injury and improve wound healing. Recombinant human growth hormone (rhGH) has been shown to reduce loss of body weight, stimulate protein synthesis, increase epithelial cell proliferation, and accelerate wound healing. Accelerated wound closure reduces the risk of infection, shortens hospital stay, and lowers overall medical costs. Current investigations are in progress to determine the effects of rhGH on anabolic growth arrests experienced by paediatric burn survivors.

Original languageEnglish (US)
Pages (from-to)29-31
Number of pages3
JournalHormone Research
Volume45
Issue numberSUPPL. 1
StatePublished - Jun 1996
Externally publishedYes

Fingerprint

Growth Hormone
Human Growth Hormone
Wound Healing
Wounds and Injuries
Pediatrics
Therapeutics
Survivors
Length of Stay
Epithelial Cells
Body Weight
Cell Proliferation
Clinical Trials
Costs and Cost Analysis
Growth
Infection
Proteins

Keywords

  • Burns
  • Growth hormone
  • Hypermetabolism
  • Insulin
  • Insulin-like growth factor
  • Paediatric

ASJC Scopus subject areas

  • Endocrinology

Cite this

Herndon, D., Pierre, E. J., Stokes, K. N., & Barrow, R. E. (1996). Growth hormone treatment for burned children. Hormone Research, 45(SUPPL. 1), 29-31.

Growth hormone treatment for burned children. / Herndon, David; Pierre, E. J.; Stokes, K. N.; Barrow, R. E.

In: Hormone Research, Vol. 45, No. SUPPL. 1, 06.1996, p. 29-31.

Research output: Contribution to journalArticle

Herndon, D, Pierre, EJ, Stokes, KN & Barrow, RE 1996, 'Growth hormone treatment for burned children', Hormone Research, vol. 45, no. SUPPL. 1, pp. 29-31.
Herndon D, Pierre EJ, Stokes KN, Barrow RE. Growth hormone treatment for burned children. Hormone Research. 1996 Jun;45(SUPPL. 1):29-31.
Herndon, David ; Pierre, E. J. ; Stokes, K. N. ; Barrow, R. E. / Growth hormone treatment for burned children. In: Hormone Research. 1996 ; Vol. 45, No. SUPPL. 1. pp. 29-31.
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