Guaroa virus infection among humans in Bolivia and Peru

Patricia V. Aguilar; Amy C. Morrison; Claudio Rocha; Douglas M. Watts; Luis Beingolea; Victor Suarez; Jorge Vargas; Cristhopher Cruz; Carolina Guevara; Joel M. Montgomery; Robert B. Tesh; Tadeusz J. Kochel

doi:10.4269/ajtmh.2010.10-0116

Guaroa virus infection among humans in Bolivia and Peru

Patricia V. Aguilar, Amy C. Morrison, Claudio Rocha, Douglas M. Watts, Luis Beingolea, Victor Suarez, Jorge Vargas, Cristhopher Cruz, Carolina Guevara, Joel M. Montgomery, Robert B. Tesh, Tadeusz J. Kochel

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

Guaroa virus (GROV) was first isolated from humans in Colombia in 1959. Subsequent isolates of the virus have been recovered from febrile patients and mosquitoes in Brazil, Colombia, and Panama; however, association of the virus with human disease has been unclear. As part of a study on the etiology of febrile illnesses in Peru and Bolivia, 14 GROV strains were isolated from patients with febrile illnesses, and 3 additional cases were confirmed by IgM seroconversion. The prevalence rate of GROV antibodies among Iquitos residents was 13%; the highest rates were among persons with occupations such as woodcutters, fisherman, and oil-field workers. Genetic characterization of representative GROV isolates indicated that strains from Peru and Bolivia form a monophyletic group that can be distinguished from strains isolated earlier in Brazil and Colombia. This study confirms GROV as a cause of febrile illness in tropical regions of Central and South America.

Original language	English (US)
Pages (from-to)	714-721
Number of pages	8
Journal	American Journal of Tropical Medicine and Hygiene
Volume	83
Issue number	3
DOIs	https://doi.org/10.4269/ajtmh.2010.10-0116
State	Published - Sep 2010
Externally published	Yes

ASJC Scopus subject areas

Infectious Diseases
Virology
Parasitology

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title = "Guaroa virus infection among humans in Bolivia and Peru",

abstract = "Guaroa virus (GROV) was first isolated from humans in Colombia in 1959. Subsequent isolates of the virus have been recovered from febrile patients and mosquitoes in Brazil, Colombia, and Panama; however, association of the virus with human disease has been unclear. As part of a study on the etiology of febrile illnesses in Peru and Bolivia, 14 GROV strains were isolated from patients with febrile illnesses, and 3 additional cases were confirmed by IgM seroconversion. The prevalence rate of GROV antibodies among Iquitos residents was 13%; the highest rates were among persons with occupations such as woodcutters, fisherman, and oil-field workers. Genetic characterization of representative GROV isolates indicated that strains from Peru and Bolivia form a monophyletic group that can be distinguished from strains isolated earlier in Brazil and Colombia. This study confirms GROV as a cause of febrile illness in tropical regions of Central and South America.",

author = "Aguilar, {Patricia V.} and Morrison, {Amy C.} and Claudio Rocha and Watts, {Douglas M.} and Luis Beingolea and Victor Suarez and Jorge Vargas and Cristhopher Cruz and Carolina Guevara and Montgomery, {Joel M.} and Tesh, {Robert B.} and Kochel, {Tadeusz J.}",

year = "2010",

month = sep,

doi = "10.4269/ajtmh.2010.10-0116",

language = "English (US)",

volume = "83",

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T1 - Guaroa virus infection among humans in Bolivia and Peru

AU - Aguilar, Patricia V.

AU - Morrison, Amy C.

AU - Rocha, Claudio

AU - Watts, Douglas M.

AU - Beingolea, Luis

AU - Suarez, Victor

AU - Vargas, Jorge

AU - Cruz, Cristhopher

AU - Guevara, Carolina

AU - Montgomery, Joel M.

AU - Tesh, Robert B.

AU - Kochel, Tadeusz J.

PY - 2010/9

Y1 - 2010/9

N2 - Guaroa virus (GROV) was first isolated from humans in Colombia in 1959. Subsequent isolates of the virus have been recovered from febrile patients and mosquitoes in Brazil, Colombia, and Panama; however, association of the virus with human disease has been unclear. As part of a study on the etiology of febrile illnesses in Peru and Bolivia, 14 GROV strains were isolated from patients with febrile illnesses, and 3 additional cases were confirmed by IgM seroconversion. The prevalence rate of GROV antibodies among Iquitos residents was 13%; the highest rates were among persons with occupations such as woodcutters, fisherman, and oil-field workers. Genetic characterization of representative GROV isolates indicated that strains from Peru and Bolivia form a monophyletic group that can be distinguished from strains isolated earlier in Brazil and Colombia. This study confirms GROV as a cause of febrile illness in tropical regions of Central and South America.

AB - Guaroa virus (GROV) was first isolated from humans in Colombia in 1959. Subsequent isolates of the virus have been recovered from febrile patients and mosquitoes in Brazil, Colombia, and Panama; however, association of the virus with human disease has been unclear. As part of a study on the etiology of febrile illnesses in Peru and Bolivia, 14 GROV strains were isolated from patients with febrile illnesses, and 3 additional cases were confirmed by IgM seroconversion. The prevalence rate of GROV antibodies among Iquitos residents was 13%; the highest rates were among persons with occupations such as woodcutters, fisherman, and oil-field workers. Genetic characterization of representative GROV isolates indicated that strains from Peru and Bolivia form a monophyletic group that can be distinguished from strains isolated earlier in Brazil and Colombia. This study confirms GROV as a cause of febrile illness in tropical regions of Central and South America.

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JO - American Journal of Tropical Medicine and Hygiene

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Guaroa virus infection among humans in Bolivia and Peru

Abstract

ASJC Scopus subject areas

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