Hantavirus pulmonary syndrome associated with Monongahela virus, Pennsylvania

Luther V. Rhodes, Cinnia Huang, Angela J. Sanchez, Stuart T. Nichol, Sherif R. Zaki, Thomas Ksiazek, J. G. Humphreys, James J. Freeman, Kenneth R. Knecht

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

The first two recognized cases of rapidly fatal hantavirus pulmonary syndrome in Pennsylvania occurred within an 8-month period in 1997. Illness in the two patients was confirmed by immunohistochemical techniques on autopsy material. Reverse transcription-polymerase chain reaction analysis of tissue from one patient and environmentally associated Peromyscus leucopus (white-footed mouse) identified the Monongahela virus variant. Physicians should be vigilant for such Monongahela virus-associated cases in the eastern United States and Canada, particularly in the Appalachian region.

Original languageEnglish (US)
Pages (from-to)616-621
Number of pages6
JournalEmerging Infectious Diseases
Volume6
Issue number6
StatePublished - 2000
Externally publishedYes

Fingerprint

Hantavirus Pulmonary Syndrome
Peromyscus
Appalachian Region
Viruses
Reverse Transcription
Canada
Autopsy
Physicians
Polymerase Chain Reaction

ASJC Scopus subject areas

  • Microbiology (medical)

Cite this

Rhodes, L. V., Huang, C., Sanchez, A. J., Nichol, S. T., Zaki, S. R., Ksiazek, T., ... Knecht, K. R. (2000). Hantavirus pulmonary syndrome associated with Monongahela virus, Pennsylvania. Emerging Infectious Diseases, 6(6), 616-621.

Hantavirus pulmonary syndrome associated with Monongahela virus, Pennsylvania. / Rhodes, Luther V.; Huang, Cinnia; Sanchez, Angela J.; Nichol, Stuart T.; Zaki, Sherif R.; Ksiazek, Thomas; Humphreys, J. G.; Freeman, James J.; Knecht, Kenneth R.

In: Emerging Infectious Diseases, Vol. 6, No. 6, 2000, p. 616-621.

Research output: Contribution to journalArticle

Rhodes, LV, Huang, C, Sanchez, AJ, Nichol, ST, Zaki, SR, Ksiazek, T, Humphreys, JG, Freeman, JJ & Knecht, KR 2000, 'Hantavirus pulmonary syndrome associated with Monongahela virus, Pennsylvania', Emerging Infectious Diseases, vol. 6, no. 6, pp. 616-621.
Rhodes LV, Huang C, Sanchez AJ, Nichol ST, Zaki SR, Ksiazek T et al. Hantavirus pulmonary syndrome associated with Monongahela virus, Pennsylvania. Emerging Infectious Diseases. 2000;6(6):616-621.
Rhodes, Luther V. ; Huang, Cinnia ; Sanchez, Angela J. ; Nichol, Stuart T. ; Zaki, Sherif R. ; Ksiazek, Thomas ; Humphreys, J. G. ; Freeman, James J. ; Knecht, Kenneth R. / Hantavirus pulmonary syndrome associated with Monongahela virus, Pennsylvania. In: Emerging Infectious Diseases. 2000 ; Vol. 6, No. 6. pp. 616-621.
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