Hematoma-directed ultrasound-guided (HUG) breast lumpectomy

Margaret Thompson, Ronda Henry-Tillman, Aaron Margulies, Jeff Thostenson, Gwen Bryant-Smith, Robert Fincher, Soheila Korourian, Vicki Klimberg

Research output: Contribution to journalArticle

48 Scopus citations

Abstract

Background: Needle localization breast biopsy (NLBB) is presently the primary means of localizing non-palpable lesions. Disadvantages of NLBB include vasovagal episodes, patient discomfort, and miss rates. Because hematomas naturally fill the cavity after vacuum-assisted breast biopsies (VABB), we hypothesized that ultrasound (US) could be used to find and accurately excise the actual biopsy site of non-palpable breast lesions without a needle. Methods: This is a retrospective study from January 2000 to July 2005. Electronic chart review identified patients with non-palpable breast lesions detected by means of mammogram who then underwent lumpectomy via NLBB or the hematoma-directed ultrasound-guided technique (HUG). HUG involved localizing the hematoma with a 7.5-MHz US probe and using the "line of sight" technique straight down toward the chest wall. A block of tissue encompassing the hematoma was then excised. Results: Localization procedures were performed in 186 patients-63 (34%) via needle localization and 123 (66%) via HUG. The previous VABB site in 100% of patients was successfully excised using HUG, 65 of 123 (53%) were benign and 58 of 123 (47%) were malignant; margins were positive in 13 of these 58 (22%). NLBB was successful in 100% of patients, 44 of 63 (70%) were benign and 19 of 63 (30%) were malignant; margins were positive in 14 of these 19 (73%). Margin positivity was significantly higher for NLBB than HUG (P = 0.0001, Fisher Exact). Conclusions: This study suggests that HUG is more accurate in localizing non-palpable lesions than NLBB. By eliminating the additional procedure needed for NLBB, HUG may also be more time- and cost efficient. HUG makes VABB not only a less invasive diagnostic procedure, but also a localization procedure.

Original languageEnglish (US)
Pages (from-to)148-156
Number of pages9
JournalAnnals of Surgical Oncology
Volume14
Issue number1
DOIs
StatePublished - Jan 2007
Externally publishedYes

Keywords

  • Biopsy
  • Breast
  • Hematoma
  • Lumpectomy
  • Ultrasound

ASJC Scopus subject areas

  • Surgery
  • Oncology

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  • Cite this

    Thompson, M., Henry-Tillman, R., Margulies, A., Thostenson, J., Bryant-Smith, G., Fincher, R., Korourian, S., & Klimberg, V. (2007). Hematoma-directed ultrasound-guided (HUG) breast lumpectomy. Annals of Surgical Oncology, 14(1), 148-156. https://doi.org/10.1245/s10434-006-9076-y