Hemichorea in a patient with diabetic ketoacidosis

Ahmed M. Yassin, Sheetal Shroff, Shreshta D. Patel, Asif M. Paker, Megan Blanton, George R. Jackson

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Background: Chorea is a common presenting feature of metabolic disorders, including nonketotic hyperglycemia in patients with type 2 diabetes mellitus, but rarely has been reported in diabetic ketoacidosis, hypothyroidism and vitamin B12 deficiency. Methods: Review the literature for reported cases of chorea as a presenting manifestation in metabolic disorders. Results: We report a case of hemichorea in a patient with type 2 diabetes mellitus complicated by diabetic ketoacidosis. The patient had a two day history of right sided hemichorea and decreased level of consciousness. Initial laboratory studies revealed hyperglycemia, ketosis and an anion gap metabolic acidosis consistent with diabetic ketoacidosis. Once treatment was started the choreiform movements significantly improved over three weeks. Conclusion: Although DKA has been rarely reported as a trigger for chorea, it should be in the differential diagnosis of a patient presenting with an acute chorea. Given the reversible nature of this disease, early recognition and treatment are imperative.

Original languageEnglish (US)
Pages (from-to)189-191
Number of pages3
JournalJournal of the Neurological Sciences
Volume342
Issue number1-2
DOIs
StatePublished - Jul 15 2014

Fingerprint

Chorea
Diabetic Ketoacidosis
Hyperglycemia
Type 2 Diabetes Mellitus
Vitamin B 12 Deficiency
Ketosis
Acid-Base Equilibrium
Hypothyroidism
Acidosis
Consciousness
Differential Diagnosis
Therapeutics

Keywords

  • Basal ganglia
  • Chorea
  • Diabetic ketoacidosis
  • Hypothyroidism
  • Non-ketotic hyperglycemia
  • Vitamin B12 deficiency

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Medicine(all)

Cite this

Yassin, A. M., Shroff, S., Patel, S. D., Paker, A. M., Blanton, M., & Jackson, G. R. (2014). Hemichorea in a patient with diabetic ketoacidosis. Journal of the Neurological Sciences, 342(1-2), 189-191. https://doi.org/10.1016/j.jns.2014.04.038

Hemichorea in a patient with diabetic ketoacidosis. / Yassin, Ahmed M.; Shroff, Sheetal; Patel, Shreshta D.; Paker, Asif M.; Blanton, Megan; Jackson, George R.

In: Journal of the Neurological Sciences, Vol. 342, No. 1-2, 15.07.2014, p. 189-191.

Research output: Contribution to journalArticle

Yassin, AM, Shroff, S, Patel, SD, Paker, AM, Blanton, M & Jackson, GR 2014, 'Hemichorea in a patient with diabetic ketoacidosis', Journal of the Neurological Sciences, vol. 342, no. 1-2, pp. 189-191. https://doi.org/10.1016/j.jns.2014.04.038
Yassin, Ahmed M. ; Shroff, Sheetal ; Patel, Shreshta D. ; Paker, Asif M. ; Blanton, Megan ; Jackson, George R. / Hemichorea in a patient with diabetic ketoacidosis. In: Journal of the Neurological Sciences. 2014 ; Vol. 342, No. 1-2. pp. 189-191.
@article{97accf71b1f443d99b3b3709a55639e5,
title = "Hemichorea in a patient with diabetic ketoacidosis",
abstract = "Background: Chorea is a common presenting feature of metabolic disorders, including nonketotic hyperglycemia in patients with type 2 diabetes mellitus, but rarely has been reported in diabetic ketoacidosis, hypothyroidism and vitamin B12 deficiency. Methods: Review the literature for reported cases of chorea as a presenting manifestation in metabolic disorders. Results: We report a case of hemichorea in a patient with type 2 diabetes mellitus complicated by diabetic ketoacidosis. The patient had a two day history of right sided hemichorea and decreased level of consciousness. Initial laboratory studies revealed hyperglycemia, ketosis and an anion gap metabolic acidosis consistent with diabetic ketoacidosis. Once treatment was started the choreiform movements significantly improved over three weeks. Conclusion: Although DKA has been rarely reported as a trigger for chorea, it should be in the differential diagnosis of a patient presenting with an acute chorea. Given the reversible nature of this disease, early recognition and treatment are imperative.",
keywords = "Basal ganglia, Chorea, Diabetic ketoacidosis, Hypothyroidism, Non-ketotic hyperglycemia, Vitamin B12 deficiency",
author = "Yassin, {Ahmed M.} and Sheetal Shroff and Patel, {Shreshta D.} and Paker, {Asif M.} and Megan Blanton and Jackson, {George R.}",
year = "2014",
month = "7",
day = "15",
doi = "10.1016/j.jns.2014.04.038",
language = "English (US)",
volume = "342",
pages = "189--191",
journal = "Journal of the Neurological Sciences",
issn = "0022-510X",
publisher = "Elsevier",
number = "1-2",

}

TY - JOUR

T1 - Hemichorea in a patient with diabetic ketoacidosis

AU - Yassin, Ahmed M.

AU - Shroff, Sheetal

AU - Patel, Shreshta D.

AU - Paker, Asif M.

AU - Blanton, Megan

AU - Jackson, George R.

PY - 2014/7/15

Y1 - 2014/7/15

N2 - Background: Chorea is a common presenting feature of metabolic disorders, including nonketotic hyperglycemia in patients with type 2 diabetes mellitus, but rarely has been reported in diabetic ketoacidosis, hypothyroidism and vitamin B12 deficiency. Methods: Review the literature for reported cases of chorea as a presenting manifestation in metabolic disorders. Results: We report a case of hemichorea in a patient with type 2 diabetes mellitus complicated by diabetic ketoacidosis. The patient had a two day history of right sided hemichorea and decreased level of consciousness. Initial laboratory studies revealed hyperglycemia, ketosis and an anion gap metabolic acidosis consistent with diabetic ketoacidosis. Once treatment was started the choreiform movements significantly improved over three weeks. Conclusion: Although DKA has been rarely reported as a trigger for chorea, it should be in the differential diagnosis of a patient presenting with an acute chorea. Given the reversible nature of this disease, early recognition and treatment are imperative.

AB - Background: Chorea is a common presenting feature of metabolic disorders, including nonketotic hyperglycemia in patients with type 2 diabetes mellitus, but rarely has been reported in diabetic ketoacidosis, hypothyroidism and vitamin B12 deficiency. Methods: Review the literature for reported cases of chorea as a presenting manifestation in metabolic disorders. Results: We report a case of hemichorea in a patient with type 2 diabetes mellitus complicated by diabetic ketoacidosis. The patient had a two day history of right sided hemichorea and decreased level of consciousness. Initial laboratory studies revealed hyperglycemia, ketosis and an anion gap metabolic acidosis consistent with diabetic ketoacidosis. Once treatment was started the choreiform movements significantly improved over three weeks. Conclusion: Although DKA has been rarely reported as a trigger for chorea, it should be in the differential diagnosis of a patient presenting with an acute chorea. Given the reversible nature of this disease, early recognition and treatment are imperative.

KW - Basal ganglia

KW - Chorea

KW - Diabetic ketoacidosis

KW - Hypothyroidism

KW - Non-ketotic hyperglycemia

KW - Vitamin B12 deficiency

UR - http://www.scopus.com/inward/record.url?scp=84902083933&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84902083933&partnerID=8YFLogxK

U2 - 10.1016/j.jns.2014.04.038

DO - 10.1016/j.jns.2014.04.038

M3 - Article

VL - 342

SP - 189

EP - 191

JO - Journal of the Neurological Sciences

JF - Journal of the Neurological Sciences

SN - 0022-510X

IS - 1-2

ER -