Hemorrhagic fever with renal syndrome in Greece: clinical and laboratory characteristics.

A. Antoniadis, James LeDuc, N. Acritidis, S. Alexiou-Daniel, A. Kyparissi, G. A. Saviolakis

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

The clinical and laboratory characteristics of a severe form of hemorrhagic fever with renal syndrome (HFRS) in Greece are presented. Twenty-seven patients with serologically confirmed HFRS were studied; 10 required renal dialysis, six had hemorrhagic manifestations, and four died. In patients with hemorrhagic manifestations, the platelet counts were generally less than 100,000 cells/microL. In three patients findings were compatible with disseminated intravascular coagulation. Laboratory investigation showed a consistent rise in levels of serum urea nitrogen and creatinine beginning on the fifth or sixth day of illness and reaching a maximum level between the ninth and 12th days of illness. The disease in Greece more closely resembles the Asian form of HFRS (Korean hemorrhagic fever) than the Scandinavian form of the disease (nephropathia epidemica) because of the high mortality rate, the occurrence of hemorrhagic manifestations, and the severity of the clinical disease.

Original languageEnglish (US)
JournalReviews of Infectious Diseases
Volume11 Suppl 4
StatePublished - May 1989
Externally publishedYes

Fingerprint

Hemorrhagic Fever with Renal Syndrome
Greece
Sick Leave
Disseminated Intravascular Coagulation
Platelet Count
Renal Dialysis
Urea
Creatinine
Nitrogen
Mortality
Serum

ASJC Scopus subject areas

  • Microbiology (medical)

Cite this

Antoniadis, A., LeDuc, J., Acritidis, N., Alexiou-Daniel, S., Kyparissi, A., & Saviolakis, G. A. (1989). Hemorrhagic fever with renal syndrome in Greece: clinical and laboratory characteristics. Reviews of Infectious Diseases, 11 Suppl 4.

Hemorrhagic fever with renal syndrome in Greece : clinical and laboratory characteristics. / Antoniadis, A.; LeDuc, James; Acritidis, N.; Alexiou-Daniel, S.; Kyparissi, A.; Saviolakis, G. A.

In: Reviews of Infectious Diseases, Vol. 11 Suppl 4, 05.1989.

Research output: Contribution to journalArticle

Antoniadis, A, LeDuc, J, Acritidis, N, Alexiou-Daniel, S, Kyparissi, A & Saviolakis, GA 1989, 'Hemorrhagic fever with renal syndrome in Greece: clinical and laboratory characteristics.', Reviews of Infectious Diseases, vol. 11 Suppl 4.
Antoniadis A, LeDuc J, Acritidis N, Alexiou-Daniel S, Kyparissi A, Saviolakis GA. Hemorrhagic fever with renal syndrome in Greece: clinical and laboratory characteristics. Reviews of Infectious Diseases. 1989 May;11 Suppl 4.
Antoniadis, A. ; LeDuc, James ; Acritidis, N. ; Alexiou-Daniel, S. ; Kyparissi, A. ; Saviolakis, G. A. / Hemorrhagic fever with renal syndrome in Greece : clinical and laboratory characteristics. In: Reviews of Infectious Diseases. 1989 ; Vol. 11 Suppl 4.
@article{4deb248bc9a447f0ae173f2d56c0babf,
title = "Hemorrhagic fever with renal syndrome in Greece: clinical and laboratory characteristics.",
abstract = "The clinical and laboratory characteristics of a severe form of hemorrhagic fever with renal syndrome (HFRS) in Greece are presented. Twenty-seven patients with serologically confirmed HFRS were studied; 10 required renal dialysis, six had hemorrhagic manifestations, and four died. In patients with hemorrhagic manifestations, the platelet counts were generally less than 100,000 cells/microL. In three patients findings were compatible with disseminated intravascular coagulation. Laboratory investigation showed a consistent rise in levels of serum urea nitrogen and creatinine beginning on the fifth or sixth day of illness and reaching a maximum level between the ninth and 12th days of illness. The disease in Greece more closely resembles the Asian form of HFRS (Korean hemorrhagic fever) than the Scandinavian form of the disease (nephropathia epidemica) because of the high mortality rate, the occurrence of hemorrhagic manifestations, and the severity of the clinical disease.",
author = "A. Antoniadis and James LeDuc and N. Acritidis and S. Alexiou-Daniel and A. Kyparissi and Saviolakis, {G. A.}",
year = "1989",
month = "5",
language = "English (US)",
volume = "11 Suppl 4",
journal = "Clinical Infectious Diseases",
issn = "1058-4838",
publisher = "Oxford University Press",

}

TY - JOUR

T1 - Hemorrhagic fever with renal syndrome in Greece

T2 - clinical and laboratory characteristics.

AU - Antoniadis, A.

AU - LeDuc, James

AU - Acritidis, N.

AU - Alexiou-Daniel, S.

AU - Kyparissi, A.

AU - Saviolakis, G. A.

PY - 1989/5

Y1 - 1989/5

N2 - The clinical and laboratory characteristics of a severe form of hemorrhagic fever with renal syndrome (HFRS) in Greece are presented. Twenty-seven patients with serologically confirmed HFRS were studied; 10 required renal dialysis, six had hemorrhagic manifestations, and four died. In patients with hemorrhagic manifestations, the platelet counts were generally less than 100,000 cells/microL. In three patients findings were compatible with disseminated intravascular coagulation. Laboratory investigation showed a consistent rise in levels of serum urea nitrogen and creatinine beginning on the fifth or sixth day of illness and reaching a maximum level between the ninth and 12th days of illness. The disease in Greece more closely resembles the Asian form of HFRS (Korean hemorrhagic fever) than the Scandinavian form of the disease (nephropathia epidemica) because of the high mortality rate, the occurrence of hemorrhagic manifestations, and the severity of the clinical disease.

AB - The clinical and laboratory characteristics of a severe form of hemorrhagic fever with renal syndrome (HFRS) in Greece are presented. Twenty-seven patients with serologically confirmed HFRS were studied; 10 required renal dialysis, six had hemorrhagic manifestations, and four died. In patients with hemorrhagic manifestations, the platelet counts were generally less than 100,000 cells/microL. In three patients findings were compatible with disseminated intravascular coagulation. Laboratory investigation showed a consistent rise in levels of serum urea nitrogen and creatinine beginning on the fifth or sixth day of illness and reaching a maximum level between the ninth and 12th days of illness. The disease in Greece more closely resembles the Asian form of HFRS (Korean hemorrhagic fever) than the Scandinavian form of the disease (nephropathia epidemica) because of the high mortality rate, the occurrence of hemorrhagic manifestations, and the severity of the clinical disease.

UR - http://www.scopus.com/inward/record.url?scp=0024671476&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0024671476&partnerID=8YFLogxK

M3 - Article

C2 - 2568679

AN - SCOPUS:0024671476

VL - 11 Suppl 4

JO - Clinical Infectious Diseases

JF - Clinical Infectious Diseases

SN - 1058-4838

ER -