Hemostasis, coagulation abnormalities, and liver disease

Carole L. Mackavey, Robert Hanks

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations


Coagulopathy-related bleeding events are a major concern in the management of acute and chronic liver disease. The liver attempts to maintain a balance between procoagulant and anticoagulant factors, and providers struggle with poor prognostic indicators to manage bleeding and critical complications. Subtle changes in patient presentation that may require extensive provider-directed interventions, such as blood transfusions, intravenous fluid management, mitigating possible sepsis, and evaluating appropriate pharmacologic treatment, are discussed.

Original languageEnglish (US)
Pages (from-to)435-446
Number of pages12
JournalCritical care nursing clinics of North America
Issue number4
StatePublished - Dec 2013
Externally publishedYes


  • Anticoagulants
  • Coagulation abnormalities
  • Fibrinolysis
  • Hemostasis
  • Liver disease
  • Procoagulants

ASJC Scopus subject areas

  • Critical Care


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